Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | PER2 | O15055 | 6/20 | 0.33 |
| ▸ | CRY1 | Q16526 | 5/20 | 0.33 |
| ▸ | CRY2 | Q49AN0 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4585696 | 0.81 | APEX1 (0.33) | APEX1PER2CRY1CRY2 | |
| SCHEMBL3794136 | 0.73 | PER2 (0.44) | APEX1KMT2AMEN1PER2CRY1 | |
| SCHEMBL6253134 | 0.72 | PER2 (0.41) | APEX1PER2CRY1CRY2ALDH1A1 | |
| Potassium SCHEMBL5140869 | 0.72 | PER2 (0.43) | APEX1KMT2AMEN1PER2CRY1 | |
| SCHEMBL29220638 | 0.70 | CYP1A2 (0.33) | KMT2APER2CRY1CRY2ALDH1A1 | |
| SCHEMBL242395 | 0.70 | TSHR (0.42) | KMT2AMEN1PER2CRY1CRY2 | |
| SCHEMBL27702880 | 0.70 | GLA (0.49) | KMT2AMEN1PER2CRY1CRY2 | |
| SCHEMBL2495979 | 0.69 | MGLL (0.41) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL7132181 | 0.69 | ALDH1A1 (0.39) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL8276611 | 0.69 | SLC22A6 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358459-A4 | HYGIENE MONITORING | CHARM SCIENCES INC (US) | 2005-01-19 | — | — | EP | disclosed |
| EP-1358459-A2 | HYGIENE MONITORING | Charm Sciences Inc. (US) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002010708-A2 | HYGIENE MONITORING | CHARM SCIENCES, INC. (US) | 2002-02-07 | — | — | WO | disclosed |