Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.58 |
| ▸ | NR3C2 | P08235 | 11/20 | 0.50 |
| ▸ | PGR | P06401 | 6/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL379422 | 1.00 | NR3C1 (0.58) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL13623771 | 0.90 | NR3C1 (0.51) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL14587242 | 0.86 | NR3C1 (0.64) | NR3C1NR3C2 | |
| SCHEMBL379407 | 0.86 | NR3C1 (0.61) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL379408 | 0.86 | NR3C1 (0.61) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL10089057 | 0.82 | NR3C1 (0.44) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL12122089 | 0.78 | NR3C1 (0.61) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL10089085 | 0.78 | NR3C1 (0.54) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL4774775 | 0.77 | NR3C1 (0.57) | NR3C1NR3C2PGR | |
| SCHEMBL4774780 | 0.77 | NR3C1 (0.57) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2280974-B1 | STEREOSELECTIVE SYNTHESIS OF CERTAIN TRIFLUOROMETHYL-SUBSTITUTED ALCOHOLS | BOEHRINGER INGELHEIM INT (DE) | 2012-01-25 | — | — | EP | disclosed |
| US-20110275808-A1 | STEREOSELECTIVE SYNTHESIS OF CERTAIN TRIFLUOROMETHYL-SUBSTITUTED ALCOHOLS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275808-A1 | STEREOSELECTIVE SYNTHESIS OF CERTAIN TRIFLUOROMETHYL-SUBSTITUTED ALCOHOLS | ADH1A, ADH1C, ADH5 | NR3C1 132/4885NR3C2 38/4885PGR 2589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.