Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 19/20 | 0.57 |
| ▸ | NR3C2 | P08235 | 10/20 | 0.55 |
| ▸ | PGR | P06401 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4774775 | 1.00 | NR3C1 (0.57) | NR3C1NR3C2PGR | |
| SCHEMBL14587242 | 0.88 | NR3C1 (0.64) | NR3C1NR3C2 | |
| SCHEMBL13632723 | 0.87 | NR3C1 (0.50) | NR3C1NR3C2 | |
| SCHEMBL14064836 | 0.87 | NR3C1 (0.50) | NR3C1NR3C2 | |
| SCHEMBL4466741 | 0.77 | NR3C1 (0.45) | NR3C1NR3C2PGR | |
| SCHEMBL379422 | 0.77 | NR3C1 (0.58) | NR3C1NR3C2PGR | |
| SCHEMBL4772164 | 0.77 | NR3C1 (0.69) | NR3C1NR3C2 | |
| SCHEMBL4772156 | 0.77 | NR3C1 (0.69) | NR3C1NR3C2 | |
| SCHEMBL379423 | 0.77 | NR3C1 (0.58) | NR3C1NR3C2PGR | |
| SCHEMBL13632709 | 0.76 | NR3C1 (0.52) | NR3C1NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727818-B1 | STEREOSELECTIVE SYNTHESIS OF CERTAIN TRIFLUOROMETHYL-SUBSTITUTED ALCOHOLS | BOEHRINGER INGELHEIM PHARMA (US) | 2008-07-23 | — | — | EP | disclosed |
| US-7179919-B2 | Stereoselective synthesis of certain trifluoromethyl-substituted alcohols | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2007-02-20 | — | — | US | disclosed |
| EP-1727818-A1 | STEREOSELECTIVE SYNTHESIS OF CERTAIN TRIFLUOROMETHYL-SUBSTITUTED ALCOHOLS | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005090343-A1 | STEREOSELECTIVE SYNTHESIS OF CERTAIN TRIFLUOROMETHYL-SUBSTITUTED ALCOHOLS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-09-29 | — | — | WO | disclosed |
| US-20050209488-A1 | Stereoselective synthesis of certain trifluoromethyl-substituted alcohols | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209488-A1 | Stereoselective synthesis of certain trifluoromethyl-substituted alcohols | ADH1A, ADH1C, ADH5 | NR3C1 132/4885NR3C2 38/4885PGR 2589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.