Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3796441 | 0.93 | HTR1A (0.36) | ALDH1A1NPSR1GPR55L3MBTL1HTT | |
| SCHEMBL3792309 | 0.90 | LMNA (0.34) | ALDH1A1L3MBTL1HTTLMNAKMT2A | |
| SCHEMBL3798367 | 0.90 | ALDH1A1 (0.34) | ALDH1A1L3MBTL1HTTLMNAMAPT | |
| SCHEMBL3021663 | 0.88 | ALDH1A1 (0.36) | ALDH1A1NPSR1GPR55L3MBTL1HTT | |
| SCHEMBL3797570 | 0.86 | ALDH1A1 (0.32) | ALDH1A1NPSR1HTTLMNAMAPT | |
| SCHEMBL3804544 | 0.85 | HTR6 (0.32) | LMNAMMP1MMP9 | |
| SCHEMBL3799436 | 0.85 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1HTTLMNAMAPT | |
| SCHEMBL3792854 | 0.84 | TDP1 (0.34) | ALDH1A1NPSR1GPR55L3MBTL1HTT | |
| SCHEMBL3792570 | 0.83 | GRIN1 (0.33) | ALDH1A1HCRTR2KDM4E | |
| SCHEMBL3796588 | 0.82 | TXNRD1 (0.35) | ALDH1A1NPSR1GPR55L3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100173777-A1 | Piperazine Compounds Having Herbicidal Action | BASF SE (DE) | 2010-07-08 | — | — | US | claimed |
| EP-2054394-B1 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | BASF SE (DE) | 2009-11-18 | — | — | EP | claimed |
| EP-2054394-A2 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | Basf Se (DE) | 2009-05-06 | — | — | EP | claimed |
| WO-2008152072-A2 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | BASF SE (DE) | 2008-12-18 | — | — | WO | claimed |
| US-20100173777-A1 | Piperazine Compounds Having Herbicidal Action | BASF SE (DE) | 2010-07-08 | — | — | US | disclosed |
| EP-2054394-B1 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | BASF SE (DE) | 2009-11-18 | — | — | EP | disclosed |
| EP-2054394-A2 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | Basf Se (DE) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008152072-A2 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | BASF SE (DE) | 2008-12-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173777-A1 | Piperazine Compounds Having Herbicidal Action | CBR3, CBR1, CNPY2 | ALDH1A1 1174/4885NPSR1 594/4885GPR55 2522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.