Water

Water

SCHEMBL3795353

O.O.[Au].[Si]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL27608953 1.00
Ammonia Solution, Strong SCHEMBL27643163 0.87
Methane SCHEMBL28279094 0.87
Water SCHEMBL8466513 0.82
Water SCHEMBL2355031 0.82
SCHEMBL771067 0.82
Water SCHEMBL8055071 0.82
Water SCHEMBL837641 0.82
Water SCHEMBL251541 0.82
Water SCHEMBL7168086 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104353844-B Preparation method of silica/gold/ silica three-layer nano particles 西安交通大学 2017-01-11 CN claimed
CN-105510411-A Method for single cancer cell detection based on cell-microelectrode interaction UNIV SHAANXI NORMAL 2016-04-20 CN claimed
CN-116827442-A Method for realizing chiral nanometer light source, method for exciting chiral light and method for controlling chiral light signal 北京大学 2023-09-29 CN disclosed
CN-111511468-B Heterogeneous catalyst for the production of methyl methacrylate by oxidative esterification 陶氏环球技术有限责任公司 2023-07-11 CN disclosed
CN-108258058-B Preparation method of composite thin film transistor based on gold/silicon dioxide shell-core microstructure and molybdenum disulfide 福州大学 2020-08-11 CN disclosed
CN-108258058-B Preparation method of composite thin film transistor based on gold/silicon dioxide shell-core microstructure and molybdenum disulfide 福州大学 2020-08-11 CN disclosed
CN-105419802-B A kind of preparation method for heating thermometric dual-functionality nano-particle 西安交通大学 2017-06-23 CN disclosed
CN-106391005-A Preparation method of multilayered silicon dioxide particles for catalytic column 北京化大宏博应用技术研究院有限公司安庆分公司 2017-02-15 CN disclosed
CN-104353844-B Preparation method of silica/gold/ silica three-layer nano particles 西安交通大学 2017-01-11 CN disclosed
CN-104086720-B A kind of preparation method of the bivalve layer nuclear shell structure nano compound particle with cavity QILU UNIVERSITY OF TECHNOLOGY (CN) 2017-01-04 CN disclosed
CN-105510411-A Method for single cancer cell detection based on cell-microelectrode interaction UNIV SHAANXI NORMAL 2016-04-20 CN disclosed
US-20020169235-A1 Temperature-sensitive polymer/nanoshell composites for photothermally modulated drug delivery WM. MARSH RICE UNIVERSITY (US) 2002-11-14 US disclosed
US-6428811-B1 IMPLANTABLE OR INJECTABLE MATERIAL; CONTROLLED RELEASE OF MEDICATION, SUCH AS INSULIN VIA LOCALIZED HEATING FROM EXTERNAL EXPOSURE TO NEAR-IR LIGHT; NONDAMAGING TO SURROUNDING BODY TISSUE; DIABETES MELLITUS WM. MARSH RICE UNIVERSITY 2002-08-06 US disclosed
EP-1208005-A1 TEMPERATURE-SENSITIVE POLYMER/NANOSHELL COMPOSITES FOR PHOTOTHERMALLY MODULATED DRUG DELIVERY Wm. MARSH RICE UNIVERSITY (US) 2002-05-29 EP disclosed
WO-2001005586-A1 TEMPERATURE-SENSITIVE POLYMER/NANOSHELL COMPOSITES FOR PHOTOTHERMALLY MODULATED DRUG DELIVERY WM. MARSH RICE UNIVERSITY (US) 2001-01-25 WO disclosed
EP-0491502-A2 Vertical-cavity surface-emitting laser with non-epitaxial multilayered dielectric reflectors located on both surfaces AT&T Corp. (US) 1992-06-24 EP disclosed
US-5063569-A Vertical-cavity surface-emitting laser with non-epitaxial multilayered dielectric reflectors located on both surfaces AT&T BELL LABORATORIES (US) 1991-11-05 US disclosed
US-4716071-A Method of ensuring adhesion of chemically vapor deposited oxide to gold integrated circuit interconnect lines HARRIS CORPORATION (US) 1987-12-29 US disclosed
US-4713260-A Method of ensuring adhesion of chemically vapor deposited oxide to gold integrated circuit interconnect lines HARRIS CORPORATION 1987-12-15 US disclosed
US-4624749-A Electrodeposition of submicrometer metallic interconnect for integrated circuits HARRIS CORPORATION (US) 1986-11-25 US disclosed