Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 17/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13075524 | 0.79 | PTGES (0.57) | PTGESGRM5PTGS1 | |
| SCHEMBL3794537 | 0.77 | PTGES (0.54) | PTGESGRM5PTGS1 | |
| SCHEMBL3798131 | 0.73 | PTGES (0.43) | PTGES | |
| SCHEMBL3795873 | 0.73 | PTGES (0.49) | PTGES | |
| SCHEMBL12478777 | 0.70 | PTGES (0.77) | PTGESPTGS1 | |
| SCHEMBL2361302 | 0.70 | PTGES (0.58) | PTGES | |
| SCHEMBL30873473 | 0.68 | GRM5 (0.58) | PTGESGRM5 | |
| SCHEMBL3800830 | 0.67 | PTGES (0.54) | PTGESPTGS1SCN2A | |
| SCHEMBL3799817 | 0.66 | PDE4A (0.39) | PTGES | |
| SCHEMBL1476835 | 0.65 | CHRNB2 (0.51) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127152-A2 | COMPOUNDS AND COMPOSITIONS AS MICROSOMAL PROSTAGLANDIN E SYNTHASE-1 INHIBITORS | IRM LLC (BM) | 2010-11-04 | — | — | WO | claimed |