Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 18/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3801553 | 0.78 | PTGES (0.40) | PTGESKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL3797019 | 0.73 | PTGES (0.53) | PTGES | |
| SCHEMBL15600340 | 0.68 | CNR2 (0.39) | PTGESKDM4EALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL15552814 | 0.68 | ADK (0.41) | — | |
| SCHEMBL15552722 | 0.66 | PTGES (0.39) | PTGES | |
| SCHEMBL10300050 | 0.65 | ALDH1A1 (0.52) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL3795873 | 0.63 | PTGES (0.49) | PTGES | |
| SCHEMBL15552309 | 0.62 | PTGES (0.39) | PTGES | |
| SCHEMBL15553073 | 0.61 | PTGES (0.48) | PTGES | |
| SCHEMBL15539912 | 0.61 | PTGES (0.38) | PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127152-A2 | COMPOUNDS AND COMPOSITIONS AS MICROSOMAL PROSTAGLANDIN E SYNTHASE-1 INHIBITORS | IRM LLC (BM) | 2010-11-04 | — | — | WO | claimed |