SCHEMBL379778

SCHEMBL379778

CCCOc1cc(O)c(-c2nc(-c3ccc(C(C)(C)C)cc3C(C)(C)C)nc(-c3ccc(C(C)(C)C)cc3C(C)(C)C)n2)cc1C

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.40
ESR1 P03372 11/20 0.39
LMNA P02545 2/20 0.38
HTT P42858 2/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 1/20 0.38
ATM Q13315 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
RECQL P46063 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
KMT2A Q03164 1/20 0.35
HSP90AA1 P07900 1/20 0.34
MRGPRX4 Q96LA9 1/20 0.34
TRPV1 Q8NER1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29349867 1.00 KDM4E (0.40) KDM4EESR1LMNAHTTALDH1A1
SCHEMBL1311279 0.78 MAPT (0.42) ESR1LMNAHTTALDH1A1MAPT
SCHEMBL29633162 0.78 MAPT (0.42) ESR1LMNAHTTALDH1A1MAPT
SCHEMBL379444 0.75 NR5A1 (0.45) ALDH1A1MAPTKMT2A
SCHEMBL29351856 0.75 NR5A1 (0.45) ALDH1A1MAPTKMT2A
SCHEMBL27891329 0.72 KDM4E (0.68) KDM4EESR1LMNAHTTALDH1A1
SCHEMBL986849 0.71 KDM4E (0.49) KDM4ELMNAHTTALDH1A1MAPT
SCHEMBL25180655 0.68 HSP90AA1 (0.37) ALDH1A1MAPTTDP1RECQLKMT2A
SCHEMBL25792770 0.68 KDM4E (0.45) KDM4EHTTALDH1A1MAPTATM
SCHEMBL28789426 0.68 ESR1 (0.44) ESR1LMNAHTTALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 295 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12624265-B2 Antistatic agent, antistatic composition comprising same, antistatic resin composition comprising same, and molded article thereof ADEKA CORPORATION (JP) 2026-05-12 US disclosed
US-20260125314-A1 TRANSPARENT LAMINATE NIPPON SHEET GLASS COMPANY, LIMITED (JP) 2026-05-07 US disclosed
EP-4726011-A1 FLAME RETARDANT, COMPOSITION, AND MOLDED ARTICLE ADEKA CORPORATION (JP) 2026-04-15 EP disclosed
US-20260092163-A1 FLAME-RETARDANT COMPOSITION, FLAME-RETARDANT RESIN COMPOSITION, AND MOLDED PRODUCT ADEKA CORPORATION (JP) 2026-04-02 US disclosed
US-12540122-B2 Nucleating agent, synthetic-resin composition containing same, and molded object thereof ADEKA CORPORATION (JP) 2026-02-03 US disclosed
US-12540229-B2 Flame-retardant composition and flame-retardant synthetic resin composition ADEKA CORPORATION (JP) 2026-02-03 US disclosed
US-12528733-B2 Transparent laminate NIPPON SHEET GLASS COMPANY, LIMITED (JP) 2026-01-20 US disclosed
EP-4678699-A1 RESIN ADDITIVE, COMPOSITION, MOLDED ARTICLE AND COMPOUND ADEKA CORPORATION (JP) 2026-01-14 EP disclosed
EP-4640753-A2 NUCLEATING AGENT, SYNTHETIC-RESIN COMPOSITION CONTAINING SAME, AND MOLDED OBJECT THEREOF ADEKA CORPORATION (JP) 2025-10-29 EP disclosed
EP-4632041-A1 FLAME-RETARDANT COMPOSITION, FLAME-RETARDANT RESIN COMPOSITION AND MOLDED ARTICLE ADEKA CORPORATION (JP) 2025-10-15 EP disclosed
EP-1277794-B1 Flame-retardant resin composition ASAHI DENKA KOGYO KK (JP) 2005-04-06 EP disclosed
EP-1516907-A1 FLAME RETARDER COMPOSITION AND FLAME RETARDANT RESIN COMPOSITION CONTAINING THE COMPOSITION Asahi Denka Co., Ltd. (JP) 2005-03-23 EP disclosed
US-20040122137-A1 Ultraviolet absorber composition and resin composition stabilized with the composition ADEKA CORPORATION (JP) 2004-06-24 US disclosed
EP-1405887-A1 ULTRAVIOLET ABSORBER COMPOSITION AND RESIN COMPOSITION STABILIZED WITH THE COMPOSITION Asahi Denka Kogyo K. K. (JP) 2004-04-07 EP disclosed
US-20030088000-A1 Flame-retardant resin composition ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 2003-05-08 US disclosed
US-6555603-B1 Addition of a nitroxy compound to a low density polymer ASAHI DENKA KOGYO K.K. (JP) 2003-04-29 US disclosed
EP-1277794-A1 Flame-retardant resin composition ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 2003-01-22 EP disclosed
EP-1209190-A1 NUCLEATING AGENT ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 2002-05-29 EP disclosed
EP-1156083-A1 RESIN COMPOSITION FOR AGRICULTURAL FILM ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 2001-11-21 EP disclosed
US-6103828-A A BLENDS COMPRISING THERMOPLASTIC RESINS, THERMOSETTING RESINS AND RUBBERS, AND A POLYVINYL CYCLOHEXANE RESIN OR ACOMPOUND HAVING HYDROINDANE AS VISCOSITY MODIFIER; IMPROVES MELT FLOW, FLEXIBILITY AT A LOW TEMPERATURE, BENDING STRENGTH HITACHI CHEMICAL CO. LTD. (JP) 2000-08-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125314-A1 TRANSPARENT LAMINATE EPCAM, L1CAM, ICAM1 KDM4E 1499/4885ESR1 2563/4885LMNA 1267/4885
US-12540122-B2 Nucleating agent, synthetic-resin composition containing same, and molded object thereof NXF1, NAP1L1, POT1 KDM4E 2612/4885ESR1 2723/4885LMNA 1298/4885
US-12528733-B2 Transparent laminate DSG1, RRP15, RO60 KDM4E 407/4885ESR1 3575/4885LMNA 994/4885
US-12624265-B2 Antistatic agent, antistatic composition comprising same, antistatic resin composition comprising same, and molded article thereof SORD, SUCLA2, SUCLG1 KDM4E 1023/4885ESR1 1012/4885LMNA 2233/4885
US-12540229-B2 Flame-retardant composition and flame-retardant synthetic resin composition PAF1, RER1, POLR2A KDM4E 1337/4885ESR1 3784/4885LMNA 2491/4885
US-20260092163-A1 FLAME-RETARDANT COMPOSITION, FLAME-RETARDANT RESIN COMPOSITION, AND MOLDED PRODUCT PHOSPHO1, PAF1, PPA1 KDM4E 1566/4885ESR1 4272/4885LMNA 2518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.