Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.32 |
| ▸ | SELPLG | Q14242 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21504976 | 0.81 | ALOX5 (0.33) | ALOX5ADRA2AADRA2BCYP19A1TBXAS1 | |
| SCHEMBL29945210 | 0.81 | GABRA1 (0.41) | TSHRALOX5ADRA2AADRA2BCYP19A1 | |
| SCHEMBL826728 | 0.81 | GABRA1 (0.41) | TSHRALOX5ADRA2AADRA2BCYP19A1 | |
| SCHEMBL29985513 | 0.78 | CYP1A2 (0.41) | TSHRALOX5ADRA2AADRA2BCYP19A1 | |
| SCHEMBL19682339 | 0.78 | P2RX7 (0.36) | TSHRALOX5ADRA2AADRA2BCYP19A1 | |
| SCHEMBL16844603 | 0.78 | ADRA2A (0.39) | TSHRALOX5ADRA2AADRA2BCYP19A1 | |
| SCHEMBL20509484 | 0.78 | CYP1A2 (0.41) | TSHRALOX5ADRA2AADRA2BCYP19A1 | |
| SCHEMBL8502975 | 0.76 | ALOX5 (0.49) | TSHRALOX5SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16844606 | 0.75 | ADRA2A (0.33) | ALOX5ADRA2AADRA2BCYP19A1TBXAS1 | |
| SCHEMBL4447936 | 0.74 | ALOX5 (0.34) | ALOX5ADRA2AADRA2BCYP19A1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3371170-B1 | INDOLIN-2-ONE DERIVATIVES USEFUL IN THE TREATMENT OF CNS DISEASES | HOFFMANN LA ROCHE (CH) | 2019-07-31 | — | — | EP | disclosed |
| US-7989137-B2 | Resist composition and pattern-forming method using the same | FUJIFILM CORPORATION (JP) | 2011-08-02 | — | — | US | disclosed |
| US-7645400-B2 | Composition containing carbon nanotubes having a coating | MITSUBISHI RAYON CO., LTD. (JP) | 2010-01-12 | — | — | US | disclosed |
| US-20090321688-A1 | Carbon Nanotube Composition, Composite Having a Coated Film Composed of the Same, and Their Production Methods | MITSUBISHI RAYON CO., LTD. (JP) | 2009-12-31 | — | — | US | disclosed |
| US-20090087789-A1 | RESIST COMPOSITION AND PATTERN-FORMING METHOD USING THE SAME | FUJIFILM CORPORATION (JP) | 2009-04-02 | — | — | US | disclosed |
| US-20060052509-A1 | Composition containing carbon nanotubes having coating thereof and process for producing them | MITSUBISHI RAYON CO., LTD. (JP) | 2006-03-09 | — | — | US | disclosed |