Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL826728 | 1.00 | GABRA1 (0.41) | GABRA1GABRG2GABRB3SLC6A2GABRB2 | |
| SCHEMBL29985513 | 0.84 | CYP1A2 (0.41) | GABRA1GABRG2GABRB3SLC6A2GABRB2 | |
| SCHEMBL20509484 | 0.84 | CYP1A2 (0.41) | GABRA1GABRG2GABRB3SLC6A2GABRB2 | |
| SCHEMBL19682339 | 0.84 | P2RX7 (0.36) | GABRA1GABRG2GABRB3SLC6A2GABRB2 | |
| SCHEMBL16844603 | 0.84 | ADRA2A (0.39) | GABRA1GABRG2GABRB3SLC6A2GABRB2 | |
| SCHEMBL3797934 | 0.81 | TSHR (0.44) | SLC6A2HTR2CTSHRADRA2AADRA2B | |
| SCHEMBL25628272 | 0.81 | GPR139 (0.37) | SLC6A2ADRA2AADRA2BSLC6A4SLC6A3 | |
| SCHEMBL4447936 | 0.80 | ALOX5 (0.34) | SLC6A2ADRA2AADRA2BSLC6A4SLC6A3 | |
| SCHEMBL10367027 | 0.80 | CXCL8 (0.41) | LMNAHPGDPTGS1ADRA2AADRA2B | |
| SCHEMBL2957620 | 0.79 | ADRA2A (0.41) | SLC6A2LMNAADRA2AADRA2BSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073420-A | Preparation method of 2-phenylbenzothiophene derivative | 陕西维世诺新材料有限公司 | 2022-09-20 | — | — | CN | disclosed |