Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL787534 | 0.82 | XPO1 (0.30) | XPO1 | |
| Bicarbonate SCHEMBL3183815 | 0.76 | ALDH1A1 (0.40) | XPO1 | |
| SCHEMBL1172858 | 0.74 | XPO1 (0.33) | XPO1 | |
| SCHEMBL24939689 | 0.72 | ALDH1A1 (0.50) | ALOX15 | |
| SCHEMBL14314260 | 0.71 | MGLL (0.36) | XPO1 | |
| SCHEMBL24939824 | 0.69 | DDAH1 (0.53) | — | |
| SCHEMBL11297655 | 0.67 | XPO1 (0.32) | XPO1 | |
| SCHEMBL712319 | 0.67 | MGLL (0.38) | XPO1 | |
| SCHEMBL24398814 | 0.65 | ALDH1A1 (0.32) | — | |
| SCHEMBL2153003 | 0.64 | POLB (0.39) | XPO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100297025-A1 | Novel compositions magnetic particles covered with gem-bisphosphonate derivatives | GUERBET. | 2010-11-25 | — | — | US | disclosed |
| US-7780953-B2 | Compositions magnetic particles covered with gem-bisphosphonate derivatives | GUERBET (FR) | 2010-08-24 | — | — | US | disclosed |
| US-20040253181-A1 | Novel compositions magnetic particles covered with gem-bisphosphonate derivatives | GUERBET (FR) | 2004-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100297025-A1 | Novel compositions magnetic particles covered with gem-bisphosphonate derivatives | PHOSPHO1, SGMS2, PTEN | XPO1 1460/4885ALOX15 3122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.