Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11789192 | 0.80 | LMNA (0.44) | GABRA1GABRB2TDP1HIF1AKDM4E | |
| SCHEMBL387118 | 0.79 | GABRA1 (0.48) | GABRA1GABRB2TDP1HIF1AKDM4E | |
| SCHEMBL11405118 | 0.77 | GABRA1 (0.46) | GABRA1GABRB2TDP1HIF1ATSHR | |
| SCHEMBL8165911 | 0.77 | POLB (0.34) | GABRA1GABRB2TDP1HIF1ATSHR | |
| SCHEMBL27764282 | 0.75 | G6PD (0.49) | G6PDCASP7CASP6TDP1KDM4E | |
| SCHEMBL7594286 | 0.74 | ALDH1A1 (0.39) | GABRA1GABRB2TSHRALOX15ALDH1A1 | |
| SCHEMBL10624727 | 0.74 | GABRA1 (0.46) | G6PDCASP7CASP6GABRA1GABRB2 | |
| SCHEMBL646259 | 0.74 | CYP3A4 (0.38) | CASP7TDP1HIF1AKDM4ETSHR | |
| SCHEMBL5368315 | 0.73 | ALDH1A1 (0.30) | TDP1TSHRHPGDALDH1A1HSD17B10 | |
| SCHEMBL4163307 | 0.73 | KDM4E (0.33) | GABRA1GABRB2KDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5324298-B2 | — | — | 2013-10-23 | — | — | JP | disclosed |
| JP-2010248122-A | METHODS FOR PREPARING CARBAMATE DERIVATIVE AND HYDROXYALKYL AMINOPHENOL DERIVATIVE | SHOWA KAGAKU KOGYO CO LTD | 2010-11-04 | — | — | JP | disclosed |