SCHEMBL380274

SCHEMBL380274

CCCCO[SiH](CCCCN)OCCCC

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 8/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
ALDH1A1 P00352 1/20 0.44
TSHR P16473 1/20 0.44
EPHX1 P07099 1/20 0.44
ADRB2 P07550 1/20 0.37
ADRB1 P08588 1/20 0.37
ADRB3 P13945 1/20 0.37
CYP3A4 P08684 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
NFKB1 P19838 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8954007 0.93 DNM1 (0.40) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL569445 0.89 DNM1 (0.40) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL704381 0.89 ADRB2 (0.39) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL379680 0.87 DNM1 (0.44) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL2872173 0.85 CA12 (0.45) MEN1KMT2AALDH1A1TSHRCA1
SCHEMBL30775008 0.85 DNM1 (0.48) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL11332079 0.84 TSHR (0.40) MEN1KMT2ATSHRADRB2ADRB1
SCHEMBL5572088 0.84 TSHR (0.40) MEN1KMT2ATSHRADRB2ADRB1
SCHEMBL5575092 0.84 TSHR (0.40) MEN1KMT2ATSHRADRB2ADRB1
SCHEMBL706738 0.84 ADRB2 (0.39) ALDH1A1TSHRADRB2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2771379-A2 POLYMER, COMPOSITIONS AND PROCESS FOR PREPARING THEM DSM IP Assets B.V. (NL) 2014-09-03 EP claimed
US-20140242399-A1 POLYMER, COMPOSITIONS AND PROCESS FOR PREPARING THEM DSM IP ASSETS B.V. (NL) 2014-08-28 US claimed
WO-2013060767-A2 POLYMER, COMPOSITIONS AND PROCESS FOR PREPARING THEM DSM IP ASSETS B.V. (NL) 2013-05-02 WO claimed
US-12594700-B2 Coatings from polyisocyanurate coatings (rim) and their use in injection molding processes COVESTRO DEUTSCHLAND AG (DE) 2026-04-07 US disclosed
US-12331214-B2 Resistant 2K-PUR coatings COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2025-06-17 US disclosed
EP-3994192-B1 RESISTANT 2K-PUR COATINGS COVESTRO DEUTSCHLAND AG (DE) 2025-04-30 EP disclosed
US-20250043146-A1 MULTILAYER CONSTRUCTION ON METAL SUBSTRATES BASED ON POLYASPARTATE COATINGS COVESTRO DEUTSCHLAND AG (DE) 2025-02-06 US disclosed
EP-4453107-A1 MULTILAYER CONSTRUCTION ON METAL SUBSTRATES BASED ON POLYASPARATE COATINGS Covestro Deutschland AG (DE) 2024-10-30 EP disclosed
US-20240294798-A1 Coating Agents and Coatings That Are Obtainable Therefrom and Have Improved Resistance to Soiling and (Self-) Cleaning Properties COVESTRO DEUTSCHLAND AG (DE) 2024-09-05 US disclosed
EP-3271411-B1 POLYISOCYANATES CONTAINING SILANE GROUPS BASED ON 1,5-DIISOCYANATOPENTANE COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2024-01-10 EP disclosed
US-11795266-B2 Method for preparing a mixed silane-terminated polymer COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2023-10-24 US disclosed
EP-1022291-A1 Modified diene elastomer and its preparation Ube Industries, Ltd. (JP) 2000-07-26 EP disclosed
US-6040101-A Carrier particles for use in electrostatic image development and electrostatic image developer NIPPON SHOKUBAI CO., LTD. (JP) 2000-03-21 US disclosed
US-5728770-A COMPRISING A SILANE, ORGANOMETALLIC COMPOUMD, A COMPOUND WITH TWO FUNCTIONAL GROUPS AND A SOLVENT; EXCELLENT GAS BARRIER PROPERTIES NIPPON SHOKUBAI CO., LTD. (JP) 1998-03-17 US disclosed
EP-0798054-A2 Process for producing a coated film continuously NIPPON SHOKUBAI CO., LTD. (JP) 1997-10-01 EP disclosed
EP-0583581-B1 Process for making a silylisocyanurate OSI SPECIALTIES INC (US) 1997-05-28 EP disclosed
EP-0671450-A1 SURFACE TREATMENT COMPOSITION AND SURFACE-TREATED RESIN MOLDING NIPPON SHOKUBAI CO., LTD. (JP) 1995-09-13 EP disclosed
EP-0583581-A1 Process for making a silylisocyanurate OSi Specialties, Inc. (US) 1994-02-23 EP disclosed
US-5272247-A Polyimide precursor, cured product thereof, and processes for producing them HITACHI, LTD. (JP) 1993-12-21 US disclosed
US-5218133-A Process for making a silylisocyanurate UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12594700-B2 Coatings from polyisocyanurate coatings (rim) and their use in injection molding processes TST, C9, ESD DNM1 4874/4885MEN1 1073/4885KMT2A 1410/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.