Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 9/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | QDPR | P09417 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3803150 | 0.75 | HTR2C (0.46) | HTR2CSIGMAR1QDPRHRH3HTR2A | |
| SCHEMBL8015147 | 0.71 | SIGMAR1 (0.52) | HTR2CSIGMAR1QDPRHRH3 | |
| SCHEMBL8515362 | 0.65 | QDPR (0.40) | HTR2CSIGMAR1QDPRHTR7HTR6 | |
| SCHEMBL1199051 | 0.64 | HTR2C (1.00) | HTR2CSIGMAR1QDPRHRH3HTR2A | |
| SCHEMBL3666855 | 0.64 | HTR2C (0.39) | HTR2CSIGMAR1QDPRHRH3HTR2A | |
| SCHEMBL21361657 | 0.63 | SIGMAR1 (0.52) | HTR2CSIGMAR1QDPRHRH3 | |
| Hydrochloric Acid SCHEMBL25217174 | 0.63 | HTR2C (1.00) | HTR2CSIGMAR1QDPRHTR2AHTR7 | |
| SCHEMBL28532721 | 0.62 | HTR2C (0.44) | HTR2CSIGMAR1QDPRHRH3HTR2A | |
| SCHEMBL5341889 | 0.62 | HTR2C (0.51) | HTR2CSIGMAR1QDPRHRH3 | |
| SCHEMBL30454060 | 0.62 | HTR2C (0.51) | HTR2CSIGMAR1QDPRHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242756-A2 | PYRROLOPYRIMIDINES AND PYRROLOPYRIDINES | Novartis AG (CH) | 2010-10-27 | — | — | EP | disclosed |
| WO-2009087225-A2 | PYRROLOPYRIMIDINES AND PYRROLOPYRIDINES | NOVARTIS AG (CH) | 2009-07-16 | — | — | WO | disclosed |