Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | HTR2C | P28335 | 8/20 | 0.50 |
| ▸ | QDPR | P09417 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21361657 | 0.73 | SIGMAR1 (0.52) | SIGMAR1HTR2CQDPRHRH3KDM4E | |
| SCHEMBL3803151 | 0.71 | HTR2C (0.47) | SIGMAR1HTR2CQDPRHRH3 | |
| SCHEMBL11246723 | 0.71 | SIGMAR1 (0.50) | SIGMAR1HTR2CQDPRHRH3KDM4E | |
| SCHEMBL24052807 | 0.69 | SIGMAR1 (0.43) | SIGMAR1HTR2CQDPRHRH3KDM4E | |
| SCHEMBL918294 | 0.69 | ADRA2A (0.31) | — | |
| SCHEMBL415545 | 0.68 | SIGMAR1 (1.00) | SIGMAR1HTR2CQDPRKDM4EALDH1A1 | |
| SCHEMBL23074510 | 0.67 | SIGMAR1 (0.46) | SIGMAR1HTR2CQDPRHRH3KDM4E | |
| SCHEMBL18372897 | 0.67 | — | — | |
| SCHEMBL5542927 | 0.67 | HTR2C (0.50) | SIGMAR1HTR2CQDPRHRH3KDM4E | |
| Bromide SCHEMBL11385943 | 0.67 | SIGMAR1 (0.96) | SIGMAR1HTR2CQDPRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0969842-A1 | PHARMACEUTICAL COMPOSITION | R.P. Scherer Limited (GB) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998042344-A1 | PHARMACEUTICAL COMPOSITION | R. P. SCHERER LIMITED (GB) | 1998-10-01 | — | — | WO | disclosed |