SCHEMBL38050

SCHEMBL38050

O=C(O)C=CC1CCCC1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
NPC1 O15118 1/20 0.43
GAA P10253 1/20 0.43
TSHR P16473 2/20 0.40
TP53 P04637 2/20 0.40
EGLN1 Q9GZT9 1/20 0.40
EGLN3 Q9H6Z9 1/20 0.40
POLB P06746 1/20 0.38
GRIN1 Q05586 1/20 0.36
GRIN2B Q13224 1/20 0.36
UGT2B7 P16662 2/20 0.35
PADI4 Q9UM07 2/20 0.35
MEN1 O00255 1/20 0.34
MITF O75030 1/20 0.34
LMNA P02545 1/20 0.34
CYP3A4 P08684 1/20 0.34
MAPT P10636 1/20 0.34
ALOX15 P16050 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38049 1.00 HTT (0.43) HTTSMN1; SMN2NPC1GAATSHR
SCHEMBL4257649 1.00 HTT (0.43) HTTSMN1; SMN2NPC1GAATSHR
SCHEMBL17263955 0.97 HTT (0.47) HTTSMN1; SMN2NPC1GAATSHR
SCHEMBL1151110 0.97 HTT (0.47) HTTSMN1; SMN2NPC1GAATSHR
SCHEMBL221714 0.97 HTT (0.47) HTTSMN1; SMN2NPC1GAATSHR
SCHEMBL23749603 0.97 HTT (0.47) HTTSMN1; SMN2NPC1GAATSHR
SCHEMBL9743609 0.97 HTT (0.47) HTTSMN1; SMN2NPC1GAATSHR
SCHEMBL4599663 0.97 HTT (0.47) HTTSMN1; SMN2NPC1GAATSHR
SCHEMBL15290579 0.97 HTT (0.47) HTTSMN1; SMN2NPC1GAATSHR
SCHEMBL9063561 0.97 HTT (0.47) HTTSMN1; SMN2NPC1GAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 838 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260131506-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC (CH) 2026-05-14 US claimed
US-12595368-B2 UV/HEVL-filtering contact lenses ALCON INC. (CH) 2026-04-07 US claimed
EP-3642276-B1 POLYVINYL CHLORIDE COMPOSITIONS CONTAINING IMPACT MODIFIERS AND CALCIUM CARBONATE DOW GLOBAL TECHNOLOGIES LLC (US) 2026-03-25 EP claimed
US-12570784-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-03-10 US claimed
US-12539650-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-02-03 US claimed
EP-3994219-B1 A COATING COMPOSITION, ITS PREPARATION METHOD AND USE THEREOF BASF COATINGS GMBH (DE) 2025-10-08 EP claimed
EP-4529621-A1 UV/HEVL-FILTERING CONTACT LENSES Alcon Inc. (CH) 2025-04-02 EP claimed
EP-4514597-A1 METHOD FOR MAKING UV AND HEVL-ABSORBING OPHTHALMIC LENSES Alcon Inc. (CH) 2025-03-05 EP claimed
EP-3847220-B1 UV-CURABLE HOT MELT ADHESIVE COMPOSITIONS FOR FLOORING APPLICATIONS BASF SE (DE) 2025-03-05 EP claimed
EP-4514595-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2025-03-05 EP claimed
EP-3177784-A1 CUSHION FLOORING MATERIAL AND MANUFACTURING METHOD FOR THE SAME LG Hausys, Ltd. (KR) 2017-06-14 EP claimed
EP-2299328-B1 Coated carriers XEROX CORP (US) 2017-04-19 EP claimed
EP-2299327-B1 Coated carriers XEROX CORP (US) 2017-03-01 EP claimed
WO-2016043453-A1 CUSHION FLOORING MATERIAL AND MANUFACTURING METHOD FOR THE SAME LG HAUSYS, LTD. (KR) 2016-03-24 WO claimed
EP-2173791-B1 WATER-BASED DISPERSIONS OF HIGHLY-BRANCHED POLYMERS BASF CORP (US) 2014-06-18 EP claimed
EP-2231777-B1 CHEMICAL AND IMPACT RESISTANT THERMOPLASTIC RESIN COMPOSITION HAVING IMPROVED EXTRUDABILITY. CHEIL IND INC (KR) 2014-04-30 EP claimed
EP-2456792-B1 PROCESS FOR THE PRODUCTION OF CONDENSATION POLYMERS VIA IN-REACTOR CHAIN EXTENSION AND PRODUCTS THEREOF BASF CORP (US) 2014-03-12 EP claimed
EP-1203029-B1 PROCESS FOR THE CONTINUOUS PRODUCTION OF GEL FREE POLYMERS, AND POWDER AND LIQUID COATING APPLICATIONS CONTAINING GEL FREE POLYMERS JOHNSON POLYMER INC (US) 2004-11-10 EP claimed
EP-0590573-B1 Resin for plastic lens HITACHI CHEMICAL CO LTD (JP) 1998-01-07 EP claimed
EP-0067308-B1 NEUTRALIZING LAYER FOR COLOR TRANSFER ASSEMBLAGES EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-03-27 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12539650-B2 Method for making embedded hydrogel contact lenses INF2, CRYZ, CRYAA HTT 2427/4885SMN1; SMN2 4286/4885NPC1 4717/4885
US-12595368-B2 UV/HEVL-filtering contact lenses UACA, HSPA4L, RAD54L HTT 27/4885SMN1; SMN2 4624/4885NPC1 3998/4885
US-12570784-B2 Method for making embedded hydrogel contact lenses CRYAB, CRYZ, CRYAA HTT 3111/4885SMN1; SMN2 4766/4885NPC1 3173/4885
US-20260131506-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES CRYZ, CRYAB, CRYAA HTT 1364/4885SMN1; SMN2 4239/4885NPC1 3947/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.