Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 8/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 2/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6769310 | 0.90 | SIGMAR1 (0.47) | ALDH1A1OPRM1OPRK1TRPM8SIGMAR1 | |
| SCHEMBL3807939 | 0.84 | SIGMAR1 (0.47) | ALDH1A1OPRM1OPRK1TRPM8SIGMAR1 | |
| SCHEMBL47953 | 0.82 | SIGMAR1 (0.43) | OPRM1OPRK1SIGMAR1MRGPRX4 | |
| SCHEMBL3807880 | 0.80 | TRPM8 (0.35) | ALDH1A1TRPM8MRGPRX4TSHRSLC6A2 | |
| SCHEMBL3808261 | 0.80 | SIGMAR1 (0.47) | OPRM1OPRK1SIGMAR1MRGPRX4SLC6A2 | |
| Oxalic Acid SCHEMBL3816149 | 0.79 | KDM4E (0.40) | ALDH1A1OPRM1OPRK1SIGMAR1MRGPRX4 | |
| SCHEMBL3807722 | 0.77 | BIRC5 (0.42) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL3817509 | 0.75 | OPRM1 (0.35) | OPRM1OPRK1SIGMAR1MRGPRX4SLC6A4 | |
| SCHEMBL3818290 | 0.74 | HTT (0.47) | ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL27666022 | 0.73 | SIGMAR1 (0.40) | OPRM1OPRK1SIGMAR1MRGPRX4CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186594-B1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO LTD (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-6797726-B1 | N-alkoxyalkyl-N,N-dialkylamine derivatives or salts thereof, and remedies for nerve degeneration diseases containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-09-28 | — | — | US | disclosed |
| EP-1186594-A1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |