Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 5/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 5/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3812316 | 0.80 | OPRM1 (0.35) | OPRM1OPRK1SLC6A4 | |
| SCHEMBL3808077 | 0.75 | ALDH1A1 (0.39) | OPRM1OPRK1SIGMAR1MRGPRX4SLC6A4 | |
| SCHEMBL47953 | 0.74 | SIGMAR1 (0.43) | OPRM1OPRK1SIGMAR1MRGPRX4 | |
| SCHEMBL3808261 | 0.72 | SIGMAR1 (0.47) | OPRM1OPRK1SIGMAR1MRGPRX4SLC6A4 | |
| SCHEMBL3815885 | 0.71 | CTNNB1 (0.36) | SIGMAR1SLC6A4LTB4RLTB4R2KDM4E | |
| Oxalic Acid SCHEMBL3816149 | 0.69 | KDM4E (0.40) | OPRM1OPRK1SIGMAR1MRGPRX4KDM4E | |
| SCHEMBL3817603 | 0.69 | SIGMAR1 (0.43) | OPRM1OPRK1SIGMAR1MRGPRX4SLC6A4 | |
| SCHEMBL3812920 | 0.68 | KIF11 (0.44) | SIGMAR1HDAC6KDM4ETDP1BLM | |
| SCHEMBL3817419 | 0.68 | RAB9A (0.43) | KDM4ESMN1; SMN2MEN1RAB9AKMT2A | |
| SCHEMBL3810680 | 0.67 | SIGMAR1 (0.41) | OPRM1OPRK1SIGMAR1MRGPRX4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186594-B1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO LTD (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-6797726-B1 | N-alkoxyalkyl-N,N-dialkylamine derivatives or salts thereof, and remedies for nerve degeneration diseases containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-09-28 | — | — | US | disclosed |
| EP-1186594-A1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |