Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1128286 | 0.69 | HPGD (0.35) | HSD17B10SMN1; SMN2ALDH1A1MAOAMAOB | |
| SCHEMBL2351201 | 0.69 | CALM1 (0.46) | RAB9ASMN1; SMN2ALDH1A1NPC1TP53 | |
| SCHEMBL4302 | 0.68 | POLB (0.44) | POLBHSD17B10RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8381428 | 0.68 | MAOA (0.40) | HSD17B10SMN1; SMN2ALDH1A1MAOAMAOB | |
| SCHEMBL367099 | 0.67 | POLB (0.56) | POLBHSD17B10RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL997130 | 0.65 | POLB (0.41) | POLBHSD17B10RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14483860 | 0.65 | CYP2C19 (0.50) | POLBHSD17B10RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL332623 | 0.65 | MAOA (0.63) | POLBHSD17B10RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28647335 | 0.64 | POLB (0.44) | POLBHSD17B10RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6607295 | 0.64 | POLB (0.44) | POLBHSD17B10RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 455 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015086793-A1 | POLYMER SUPPORTED PHOSPHORIC ACIDS AND USE THEREOF AS CATALYSTS IN THE PREPARATION OF 3-INDOLYLMETHANAMINES | FUNDACIÓ INSTITUT CATALÀ D'INVESTIGACIÓ QUÍMICA (ICIQ) (ES) | 2015-06-18 | — | — | WO | claimed |
| EP-2883879-A1 | Polymer supported phosphoric acids and use thereof as catalysts in the preparation of 3-indolylmethanamines | Fundació Institut Català d'Investigació Química (ES) | 2015-06-17 | — | — | EP | claimed |
| US-20140221631-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2014-08-07 | — | — | US | claimed |
| US-8722917-B2 | Boron-containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2014-05-13 | — | — | US | claimed |
| US-20120289686-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2012-11-15 | — | — | US | claimed |
| EP-2066789-A2 | CRYSTAL STRUCTURE OF A TRNA SYNTHETASE | Anacor Pharmaceuticals, Inc. (US) | 2009-06-10 | — | — | EP | claimed |
| EP-1976536-A2 | BORON-CONTAINING SMALL MOLECULES | Anacor Pharmaceuticals, Inc. (US) | 2008-10-08 | — | — | EP | claimed |
| WO-2008070257-A9 | CRYSTAL STRUCTURE OF A TRNA SYNTHETASE | ANACOR PHARMACEUTICALS INC (US) | 2008-09-04 | — | — | WO | claimed |
| WO-2008070257-A2 | CRYSTAL STRUCTURE OF A TRNA SYNTHETASE | ANACOR PHARMACEUTICALS, INC. (US) | 2008-06-12 | — | — | WO | claimed |
| WO-2007078340-A2 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2007-07-12 | — | — | WO | claimed |
| US-20070155699-A1 | Boron-containing small molecules | ANACOR PHARMACEUTICALS (US) | 2007-07-05 | — | — | US | claimed |
| EP-1451147-A4 | AMINO ACID DERIVATIVES | PHARMACORE INC (US) | 2007-06-06 | — | — | EP | claimed |
| US-6809207-B2 | REACTING AMMONIUM FORMATE, ALDEHYDE AND ALKYL ISOCYANATE | PHARMACORE, INC. | 2004-10-26 | — | — | US | claimed |
| EP-1451147-A1 | AMINO ACID DERIVATIVES | PharmaCore, Inc, (US) | 2004-09-01 | — | — | EP | claimed |
| US-20030064976-A1 | Reacting ammonium formate, aldehyde and alkyl isocyanate | PHARMACORE, INC. | 2003-04-03 | — | — | US | claimed |
| WO-2003010130-A1 | AMINO ACID DERIVATIVES | PHARMACORE, INC. (US) | 2003-02-06 | — | — | WO | claimed |
| EP-3556758-B1 | 1,2-DIHYDRO-1,6-NAPHTHYRIDIN-2-ONE DERIVATIVES AS CDK4/6 INHIBITORS | CSTONE PHARMACEUTICALS SUZHOU CO LTD (CN) | 2024-07-17 | — | — | EP | disclosed |
| EP-3712150-B1 | MACROCYCLIC COMPOUND SERVING AS WEE1 INHIBITOR AND APPLICATIONS THEREOF | WUXI BIOCITY BIOPHARMACEUTICS CO LTD (CN) | 2024-06-12 | — | — | EP | disclosed |
| US-4970224-A | INSECTICIDES | ROHM AND HAAS COMPANY (US) | 1990-11-13 | — | — | US | disclosed |
| EP-0337815-A1 | 1-dimethylcarbamoyl-3-substituted-5-substituted-1H-1,2,4-triazoles | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-10-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221631-A1 | BORON-CONTAINING SMALL MOLECULES | ETF1, POLR1C, DPM1 | POLB 826/4885HSD17B10 2105/4885RAB9A 2224/4885 |
| US-20030064976-A1 | Reacting ammonium formate, aldehyde and alkyl isocyanate | ALDH7A1, IL4I1, ABAT | POLB 2594/4885HSD17B10 956/4885RAB9A 3374/4885 |
| US-20120289686-A1 | BORON-CONTAINING SMALL MOLECULES | ETF1, POLR1C, DPM1 | POLB 826/4885HSD17B10 2105/4885RAB9A 2224/4885 |
| US-20070155699-A1 | Boron-containing small molecules | ETF1, POLR1C, DPM1 | POLB 826/4885HSD17B10 2105/4885RAB9A 2224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.