Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIFC1 | Q9BW19 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.41 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2157680 | 0.90 | KIFC1 (0.41) | KIFC1PTPN1PTPN6GPR34RORC | |
| SCHEMBL3812444 | 0.85 | ALDH1A1 (0.36) | RORCALDH1A1MAPT | |
| SCHEMBL3815731 | 0.81 | HDAC6 (0.39) | ALDH1A1MAPT | |
| SCHEMBL3817251 | 0.81 | MAPT (0.37) | ALDH1A1MAPT | |
| SCHEMBL3814669 | 0.80 | NTRK1 (0.43) | L3MBTL1ALDH1A1GAAPPARD | |
| SCHEMBL3817340 | 0.79 | RORB (0.37) | RORCALDH1A1MAPTHTT | |
| SCHEMBL3811068 | 0.78 | KDM4E (0.39) | MAPT | |
| SCHEMBL3815360 | 0.78 | KDM4E (0.38) | ALDH1A1MAPT | |
| SCHEMBL3812533 | 0.77 | MAPT (0.38) | ALDH1A1GAAMAPT | |
| SCHEMBL3809515 | 0.76 | IKBKB (0.39) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |