Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6426884 | 0.84 | ALDH1A1 (0.50) | ALDH1A1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL3816560 | 0.78 | HSD17B1 (0.44) | KMT2ANPC1RAB9A | |
| SCHEMBL3817332 | 0.78 | BCL2L1 (0.45) | — | |
| SCHEMBL3817235 | 0.76 | HSD17B1 (0.45) | ALDH1A1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL3807205 | 0.76 | HSD17B1 (0.45) | — | |
| SCHEMBL3807569 | 0.76 | HSD17B1 (0.45) | KMT2AMEN1 | |
| SCHEMBL3812250 | 0.75 | HPGD (0.41) | ALDH1A1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL3811484 | 0.75 | ACLY (0.43) | MAPT | |
| SCHEMBL3807581 | 0.75 | HSD17B1 (0.41) | HPGDMAPTKMT2AMEN1NPC1 | |
| SCHEMBL3811571 | 0.75 | ACLY (0.54) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |