Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.59 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1097731 | 0.90 | KDM4E (0.55) | KDM4EHPGDNPC1ALDH1A1RAB9A | |
| SCHEMBL3813996 | 0.89 | MRGPRX4 (0.59) | KDM4EHPGDNPC1ALDH1A1RAB9A | |
| SCHEMBL8980720 | 0.85 | ENPP2 (0.54) | KDM4EHPGDNPC1ALDH1A1RAB9A | |
| SCHEMBL1388211 | 0.85 | PTGER1 (0.60) | HPGDNPC1RAB9ASMN1; SMN2ENPP2 | |
| SCHEMBL8980717 | 0.84 | ENPP2 (0.56) | HPGDNPC1RAB9ASMN1; SMN2ENPP2 | |
| SCHEMBL978857 | 0.84 | HTT (0.64) | NPC1ALDH1A1SMN1; SMN2SGMS2MAPT | |
| SCHEMBL2453770 | 0.84 | SGMS2 (0.58) | KDM4EHPGDNPC1ALDH1A1RAB9A | |
| SCHEMBL6564745 | 0.84 | ALDH1A1 (0.54) | KDM4EHPGDNPC1ALDH1A1RAB9A | |
| SCHEMBL27702468 | 0.83 | PARP1 (0.65) | ALDH1A1ENPP2SGMS2HTR1AADRA1A | |
| SCHEMBL454367 | 0.83 | NPC1 (0.61) | KDM4EHPGDNPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147165-A1 | NOVEL EP4 RECEPTOR AGONIST COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2009-12-10 | — | — | WO | disclosed |
| WO-2009147165-A1 | NOVEL EP4 RECEPTOR AGONIST COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2009-12-10 | — | — | WO | disclosed |