Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MRGPRX4 | Q96LA9 | 8/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960295 | 0.90 | RAB9A (0.58) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL15887756 | 0.89 | MEN1 (0.62) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL9951153 | 0.86 | MRGPRX4 (0.63) | NPC1RAB9ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL5512061 | 0.83 | PARP1 (0.60) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL978857 | 0.83 | HTT (0.64) | NPC1SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL2453770 | 0.83 | SGMS2 (0.58) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL3811276 | 0.83 | KDM4E (0.60) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL6564745 | 0.83 | ALDH1A1 (0.54) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL131382 | 0.83 | MAOB (0.55) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL13044291 | 0.82 | SGMS2 (0.55) | RAB9ASMN1; SMN2ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032546-A2 | PROCESS FOR THE PREPARATION OF SALMETEROL AND ITS INTERMEDIATES | CADILA HEALTHCARE LIMITED (IN) | 2012-03-15 | — | — | WO | disclosed |
| CN-1159797-A | Aryloxy and arylthiopropanolamine derivative suseful as beta 3-adrenoreceptor agonists and antagonists of the beta 1 and beta 2-adrenoreceptors and pharmaceutical composition thereof | SMITHKLINE BEECHAM PLC (GB) | 1997-09-17 | — | — | CN | disclosed |