Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 8/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3807191 | 0.92 | PTGDR2 (0.48) | LTB4R2PTGDR2MEN1KMT2ABACE1 | |
| SCHEMBL3809033 | 0.91 | PTGES (0.41) | LTB4R2MEN1KMT2AALOX5ALDH1A1 | |
| SCHEMBL3809437 | 0.88 | LTB4R2 (0.42) | LTB4R2MEN1KMT2AALDH1A1GAA | |
| SCHEMBL3811519 | 0.88 | BACE1 (0.41) | LTB4R2PTGDR2MEN1KMT2ABACE1 | |
| SCHEMBL3811293 | 0.88 | LTB4R2 (0.40) | LTB4R2PTGDR2MEN1KMT2ABACE1 | |
| SCHEMBL3811133 | 0.87 | LTB4R2 (0.43) | LTB4R2KMT2AALDH1A1GAAMAPT | |
| SCHEMBL3814853 | 0.86 | LTB4R2 (0.45) | LTB4R2PTGDR2 | |
| SCHEMBL3807457 | 0.85 | MLYCD (0.42) | LTB4R2PTGDR2MEN1KMT2ABACE1 | |
| SCHEMBL3815298 | 0.85 | CPB1 (0.41) | PTGDR2MEN1KMT2ABACE1 | |
| SCHEMBL3809448 | 0.84 | LTB4R2 (0.38) | LTB4R2PTGDR2MEN1KMT2ABACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |