Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | UBE2M | P61081 | 1/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3812067 | 0.93 | P2RX7 (0.39) | MEN1KMT2AMCHR1NPY1RUBE2M | |
| SCHEMBL3815986 | 0.91 | OPRM1 (0.40) | MEN1KMT2AMCHR1NPY1RCCR5 | |
| SCHEMBL3811121 | 0.91 | CYP1A2 (0.38) | NPY1RALDH1A1 | |
| SCHEMBL3812147 | 0.91 | MCHR1 (0.36) | MEN1KMT2AMCHR1NPY1RDPP4 | |
| SCHEMBL3814645 | 0.89 | ALDH1A1 (0.41) | KDM4EALDH1A1 | |
| SCHEMBL3807840 | 0.88 | ALDH1A1 (0.42) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2157793 | 0.88 | NPY1R (0.38) | MEN1KMT2AMCHR1NPY1RDPP4 | |
| SCHEMBL3807319 | 0.87 | SLC6A4 (0.43) | — | |
| SCHEMBL3817103 | 0.84 | SLC6A2 (0.41) | ALDH1A1 | |
| SCHEMBL3816594 | 0.83 | HCRTR2 (0.41) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |