Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | UBE2M | P61081 | 1/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3811326 | 0.93 | MEN1 (0.37) | MEN1KMT2AMCHR1NPY1RUBE2M | |
| SCHEMBL3815986 | 0.91 | OPRM1 (0.40) | MEN1KMT2AMCHR1NPY1R | |
| SCHEMBL3811121 | 0.91 | CYP1A2 (0.38) | NPY1RSMN1; SMN2 | |
| SCHEMBL3812147 | 0.91 | MCHR1 (0.36) | P2RX7MEN1KMT2AMCHR1NPY1R | |
| SCHEMBL3814645 | 0.89 | ALDH1A1 (0.41) | RAB9A | |
| SCHEMBL3807840 | 0.88 | ALDH1A1 (0.42) | RAB9AMEN1KMT2A | |
| SCHEMBL3807319 | 0.87 | SLC6A4 (0.43) | CHEK1 | |
| SCHEMBL2157549 | 0.87 | P2RX7 (0.40) | P2RX7RAB9AMGLLNPY1RUBE2M | |
| SCHEMBL3817103 | 0.84 | SLC6A2 (0.41) | CHEK1 | |
| SCHEMBL3809490 | 0.83 | SLC6A4 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |