Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 3/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3811326 | 0.91 | MEN1 (0.37) | MCHR1MEN1KMT2ANPY1ROPRM1 | |
| SCHEMBL3812067 | 0.91 | P2RX7 (0.39) | MCHR1MEN1KMT2ANPY1RSMN1; SMN2 | |
| SCHEMBL3815986 | 0.89 | OPRM1 (0.40) | MCHR1MEN1KMT2ANPY1ROPRM1 | |
| SCHEMBL3811121 | 0.89 | CYP1A2 (0.38) | NPY1RSMN1; SMN2SLC6A12CYP1A2CYP2D6 | |
| SCHEMBL2157799 | 0.87 | MCHR1 (0.36) | MCHR1MEN1KMT2ANPY1ROPRD1 | |
| SCHEMBL3814645 | 0.87 | ALDH1A1 (0.41) | CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL3807840 | 0.86 | ALDH1A1 (0.42) | MEN1KMT2ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3807319 | 0.85 | SLC6A4 (0.43) | TACR1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL3817103 | 0.82 | SLC6A2 (0.41) | — | |
| SCHEMBL3816621 | 0.81 | CYP1A2 (0.34) | MEN1KMT2ANPY1RCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |