SCHEMBL3811802

SCHEMBL3811802

Cc1cc(-c2ccc(-c3ccc(O)cc3)cc2)c(C)c(C)c1O

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SENP1 Q9P0U3 1/20 0.47
ESR1 P03372 8/20 0.44
ESR2 Q92731 6/20 0.44
ABL1 P00519 3/20 0.41
ABCB1 P08183 3/20 0.41
BCR P11274 3/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
MGAM O43451 1/20 0.40
GAA P10253 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
HSD17B1 P14061 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
ALOX5 P09917 1/20 0.39
USP7 Q93009 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17060497 0.92 CA1 (0.46) SENP1ESR1ESR2MEN1KMT2A
SCHEMBL29135063 0.83 SENP1 (0.45) SENP1ESR1ESR2ABL1ABCB1
SCHEMBL1513631 0.82 ESR2 (0.52) ESR2MEN1KMT2AGAACA1
SCHEMBL3752346 0.79 CA1 (0.59) ESR1ESR2MEN1KMT2AGAA
SCHEMBL10190451 0.78 ESR2 (0.56) SENP1ESR1ESR2ABL1ABCB1
SCHEMBL1176388 0.78 CA1 (0.48) ESR1ESR2MEN1KMT2AGAA
SCHEMBL29429119 0.78 CA1 (0.48) ESR1ESR2MEN1KMT2AGAA
Phenol SCHEMBL4666810 0.78 TDP1 (0.46) SENP1ESR2MEN1KMT2AGAA
SCHEMBL16581453 0.78 ALDH1A1 (0.41) ESR1ESR2MEN1KMT2AGAA
SCHEMBL503537 0.76 CA1 (0.70) SENP1ESR1ESR2ABL1ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1375461-B1 DIPHENOL AND PROCESS FOR PRODUCING THE SAME HONSHU CHEMICAL IND (JP) 2009-08-05 EP claimed
EP-1375461-B1 DIPHENOL AND PROCESS FOR PRODUCING THE SAME HONSHU CHEMICAL IND (JP) 2009-08-05 EP disclosed
US-6872858-B2 Diphenol and process for producing the same HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2005-03-29 US disclosed
EP-1375461-A1 DIPHENOL AND PROCESS FOR PRODUCING THE SAME Honshu Chemical Industry Co. Ltd. (JP) 2004-01-02 EP disclosed