Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 8/20 | 0.58 |
| ▸ | PYCR1 | P32322 | 7/20 | 0.58 |
| ▸ | MAOB | P27338 | 7/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10643116 | 0.76 | TSHR (0.42) | MAOAPYCR1MAOBLMNATSHR | |
| Pargyline SCHEMBL18036659 | 0.73 | PYCR1 (1.00) | MAOAPYCR1MAOBLMNATSHR | |
| Pargyline SCHEMBL2045 | 0.73 | PYCR1 (1.00) | MAOAPYCR1MAOBLMNATSHR | |
| SCHEMBL8392822 | 0.72 | — | — | |
| Pargyline SCHEMBL121111 | 0.72 | LMNA (1.00) | MAOAPYCR1MAOBLMNATSHR | |
| Pargyline SCHEMBL7363311 | 0.72 | PYCR1 (0.96) | MAOAPYCR1MAOBLMNATSHR | |
| SCHEMBL1176965 | 0.71 | MAOA (0.67) | MAOAPYCR1MAOBLMNATSHR | |
| Hydrochloric Acid SCHEMBL28077090 | 0.69 | LMNA (0.68) | MAOAPYCR1MAOBLMNATSHR | |
| SCHEMBL5982497 | 0.68 | MAOB (0.53) | MAOAPYCR1MAOBLMNATSHR | |
| SCHEMBL7283026 | 0.68 | SIGMAR1 (0.62) | MAOAPYCR1MAOBLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010086860-A2 | NEUROPROTECTIVE MULTIFUNCTIONAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2010-08-05 | — | — | WO | disclosed |