Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 12/20 | 0.50 |
| ▸ | MAOB | P27338 | 12/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3818357 | 0.88 | SIGMAR1 (0.65) | MAOAMAOBSIGMAR1ACHEHTR1A | |
| Hydrochloric Acid SCHEMBL3812840 | 0.86 | SIGMAR1 (0.63) | MAOAMAOBSIGMAR1ACHEHTR1A | |
| SCHEMBL3818271 | 0.81 | HTR1B (0.43) | — | |
| Oxalic Acid SCHEMBL3812294 | 0.78 | KDM4E (0.42) | — | |
| SCHEMBL8773399 | 0.76 | MAOA (0.52) | MAOAMAOBSIGMAR1ACHEHTR1A | |
| SCHEMBL12043924 | 0.73 | MAOA (0.55) | MAOAMAOBSIGMAR1ACHE | |
| SCHEMBL27767743 | 0.69 | SIGMAR1 (0.61) | MAOAMAOBSIGMAR1ACHE | |
| SCHEMBL3808206 | 0.68 | SIGMAR1 (0.44) | SIGMAR1 | |
| SCHEMBL3815395 | 0.68 | ALDH1A1 (0.41) | SIGMAR1HTR1ASLC6A4 | |
| Hydrochloric Acid SCHEMBL3812837 | 0.67 | KMT2A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186594-B1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO LTD (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-6797726-B1 | N-alkoxyalkyl-N,N-dialkylamine derivatives or salts thereof, and remedies for nerve degeneration diseases containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-09-28 | — | — | US | disclosed |
| EP-1186594-A1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |