SCHEMBL3818271

SCHEMBL3818271

CN(C)CCOCCc1ccc2occc2c1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTR1B P28222 4/20 0.43
CA2 P00918 3/20 0.36
CA12 O43570 2/20 0.36
HRH3 Q9Y5N1 1/20 0.36
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA7 P36544 1/20 0.35
CHRM2 P08172 2/20 0.35
CHRM1 P11229 2/20 0.35
CHRM3 P20309 2/20 0.35
CYP2A6 P11509 2/20 0.34
ADRB2 P07550 1/20 0.34
ADRB1 P08588 1/20 0.34
MET P08581 1/20 0.34
CTNNB1 P35222 1/20 0.33
WNT3A P56704 1/20 0.33
OPRL1 P41146 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxalic Acid SCHEMBL3812294 0.92 KDM4E (0.42) HTR1BCTNNB1WNT3A
SCHEMBL3808206 0.86 SIGMAR1 (0.44) HTR1BCA2HRH3CHRNB4CHRNA3
SCHEMBL3815395 0.85 ALDH1A1 (0.41) HTR1BCA2CA12CHRNB4CHRNA3
SCHEMBL3812975 0.81 MAOA (0.50)
Oxalic Acid SCHEMBL3817410 0.80 SIGMAR1 (0.42) HTR1BCHRM2CHRM1CTNNB1WNT3A
SCHEMBL10507927 0.79 HTR1B (0.50) HTR1BCA2CA12CHRNB4CHRNA3
SCHEMBL48789 0.78 HTR1B (0.41) HTR1BCHRNB4CHRNA3CHRNA7CHRM2
SCHEMBL3811751 0.76 SIGMAR1 (0.57) HRH3CYP2A6
SCHEMBL12344285 0.75 CYP2A6 (0.45) HTR1BCA2CA12CHRNB4CHRNA3
SCHEMBL10508698 0.75 KCNA3 (0.43) HTR1BCTNNB1WNT3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1186594-B1 N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME TOYAMA CHEMICAL CO LTD (JP) 2009-08-05 EP disclosed
US-6797726-B1 N-alkoxyalkyl-N,N-dialkylamine derivatives or salts thereof, and remedies for nerve degeneration diseases containing the same TOYAMA CHEMICAL CO., LTD. (JP) 2004-09-28 US disclosed
EP-1186594-A1 N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME TOYAMA CHEMICAL CO., LTD. (JP) 2002-03-13 EP disclosed