Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 12/20 | 0.52 |
| ▸ | MAOB | P27338 | 12/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12043924 | 0.86 | MAOA (0.55) | MAOAMAOBSIGMAR1FTOACHE | |
| SCHEMBL3818357 | 0.77 | SIGMAR1 (0.65) | MAOAMAOBSIGMAR1ACHEHTR1A | |
| SCHEMBL24758096 | 0.76 | MAOA (0.46) | MAOAMAOBSIGMAR1FTOACHE | |
| Hydrochloric Acid SCHEMBL3812840 | 0.76 | SIGMAR1 (0.63) | MAOAMAOBSIGMAR1ACHEHTR1A | |
| SCHEMBL3812975 | 0.76 | MAOA (0.50) | MAOAMAOBSIGMAR1ACHEHTR1A | |
| SCHEMBL12386444 | 0.75 | STS (0.59) | MTNR1A | |
| SCHEMBL30768030 | 0.75 | MAOA (0.50) | MAOAMAOBFTOACHEDYRK1A | |
| SCHEMBL3792011 | 0.75 | HTR1B (0.55) | DYRK1A | |
| SCHEMBL2976539 | 0.73 | SIGMAR1 (0.73) | MAOAMAOBSIGMAR1ACHE | |
| SCHEMBL8773487 | 0.73 | MTNR1A (0.53) | MAOAMAOBMTNR1AHTR1ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8778970-B2 | Benzyl piperidine compound | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2014-07-15 | — | — | US | disclosed |
| US-20120130077-A1 | BENZYL PIPERIDINE COMPOUND | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120130077-A1 | BENZYL PIPERIDINE COMPOUND | HTR1D, HTR1A, HTR1B | MAOA 104/4885MAOB 75/4885SIGMAR1 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.