SCHEMBL381316

SCHEMBL381316

CC(=O)OC(C)C.CCCCCCCCCCCCCCCCC(CCCC)(CCCC)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
TSHR P16473 1/20 0.45
PRKCA P17252 2/20 0.37
FAAH O00519 3/20 0.36
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CES2 O00748 1/20 0.35
PAM P19021 2/20 0.34
ACE2 Q9BYF1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid Methyl Ester SCHEMBL8869579 0.83 EPHX1 (0.44) TSHRFAAHMEN1MAPTKMT2A
Isopropyl Myristate SCHEMBL31620684 0.83 LMNA (0.72) LMNATSHRPRKCAMEN1MAPT
SCHEMBL19066786 0.82 CES2 (0.47) TSHRMEN1KMT2ACES2
SCHEMBL1115965 0.82 CES2 (0.47) TSHRMEN1KMT2ACES2
SCHEMBL1898129 0.82 CES2 (0.47) TSHRMEN1KMT2ACES2
SCHEMBL168633 0.82 CES2 (0.47) TSHRMEN1KMT2ACES2
Octane SCHEMBL10883673 0.82 TSHR (0.67) LMNATSHRPRKCAFAAHMEN1
SCHEMBL20563871 0.82 CES2 (0.47) TSHRMEN1KMT2ACES2
SCHEMBL20853607 0.82 CES2 (0.47) TSHRMEN1KMT2ACES2
Heptane SCHEMBL2123028 0.82 TSHR (0.67) LMNATSHRPRKCAFAAHMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8211455-B2 Implantable or insertable medical devices for controlled delivery of a therapeutic agent BOSTON SCIENTIFIC SCIMED, INC. (US) 2012-07-03 US disclosed
EP-1513565-B1 IMPLANTABLE OR INSERTABLE MEDICAL DEVICES FOR CONTROLLED DELIVERY OF A THERAPEUTIC AGENT BOSTON SCIENT LTD (BB) 2012-01-25 EP disclosed
US-20110123594-A1 Implantable or Insertable Medical Devices For Controlled Delivery of a Therapeutic Agent BOSTON SCIENTIFIC SCIMED, INC. (US) 2011-05-26 US disclosed
US-7939094-B2 Comprises implantable/insertable implants (catheter, stents) BOSTON SCIENTIFIC SCIMED, INC. (US) 2011-05-10 US disclosed
US-7901702-B2 Implantable or insertable medical devices for controlled delivery of a therapeutic agent BOSTON SCIENTIFIC SCIMED, INC. (US) 2011-03-08 US disclosed
US-7901726-B2 Porous medical articles for therapeutic agent delivery BOSTON SCIENTIFIC SCIMED, INC. (US) 2011-03-08 US disclosed
WO-2009032665-A2 POROUS MEDICAL ARTICLES FOR THERAPEUTIC AGENT DELIVERY BOSTON SCIENTIFIC SCIMED, INC. (US) 2009-03-12 WO disclosed
US-20090061071-A1 Porous medical articles for therapeutic agent delivery BOSTON SCIENTIFIC SCIMED, INC. (US) 2009-03-05 US disclosed
US-20080311173-A1 IMPLANTABLE OR INSERTABLE MEDICAL DEVICES FOR CONTROLLED DELIVERY OF A THERAPEUTIC AGENT BOSTON SCIENTIFIC SCIMED, INC. (US) 2008-12-18 US disclosed
US-20070003599-A1 Implantable or insertable medical devices for controlled delivery of a therapeutic agent SCHWARZ MARLENE C 2007-01-04 US disclosed
WO-2004000380-A1 IMPLATABLE OR INSERTABLE MEDICAL DEVICES FOR CONTROLLED DELIVERY OF A THERAPEUTIC AGENT SCIMED LIFE SYSTEMS, INC. (US) 2003-12-31 WO disclosed
WO-2004000267-A1 METHOD FOR MODULATION OF DRUG RELEASE FROM MULTIPHASE IMPLANTABLE OR INSERTABLE MEDICAL DEVICES AND A PROCESS FOR MANUFACTURING SUCH DEVICES SCIMED LIFE SYTEMS, INC. (US) 2003-12-31 WO disclosed
WO-2004000381-A1 IMPLANTABLE OR INSERTABLE MEDICAL DEVICES FOR CONTROLLED DELIVERY OF A THERAPEUTIC AGENT SCIMED LIFE SYSTEMS, INC. (US) 2003-12-31 WO disclosed
WO-2004000384-A1 IMPLANTABLE OR INSERTABLE MEDICAL DEVICES FOR CONTROLLED DELIVERY OF A THERAPEUTIC AGENT SCIMED LIFE SYSTEMS, INC. (US) 2003-12-31 WO disclosed
US-20030235603-A1 Multiphase polymeric drug release region BOSTON SCIENTIFIC SCIMED, INC. 2003-12-25 US disclosed
US-20030236514-A1 Implantable or insertable medical devices for controlled delivery of a therapeutic agent BOSTON SCIENTIFIC SCIMED, INC. 2003-12-25 US disclosed
US-20030236513-A1 Implantable or insertable medical devices for controlled delivery of a therapeutic agent SCIMED LIFE SYSTEMS, INC. 2003-12-25 US disclosed
US-20030235602-A1 Implantable or insertable medical devices for controlled delivery of a therapeutic agent BOSTON SCIENTIFIC SCIMED, INC. 2003-12-25 US disclosed
WO-2003090806-A1 MODULATION OF THERAPEUTIC AGENT RELEASE FROM A POLYMERIC CARRIER USING SOLVENT-BASED TECHNIQUES SCIMED LIFE SYSTEMS, INC. (US) 2003-11-06 WO disclosed
US-20030203000-A1 Modulation of therapeutic agent release from a polymeric carrier using solvent-based techniques BOSTON SCIENTIFIC SCIMED, INC. 2003-10-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030203000-A1 Modulation of therapeutic agent release from a polymeric carrier using solvent-based techniques ABCB11, LPXN, LIPA LMNA 3497/4885TSHR 1872/4885PRKCA 2257/4885
US-20030235603-A1 Multiphase polymeric drug release region ABCB11, ABCB1, PIK3R1 LMNA 1886/4885TSHR 2123/4885PRKCA 2390/4885
US-20030236514-A1 Implantable or insertable medical devices for controlled delivery of a therapeutic agent MLEC, CA6, MIF LMNA 1397/4885TSHR 4429/4885PRKCA 1023/4885
US-20110123594-A1 Implantable or Insertable Medical Devices For Controlled Delivery of a Therapeutic Agent MIF, PAICS, IDUA LMNA 2922/4885TSHR 2108/4885PRKCA 2296/4885
US-20030236513-A1 Implantable or insertable medical devices for controlled delivery of a therapeutic agent PAICS, MIF, PGF LMNA 1827/4885TSHR 2465/4885PRKCA 671/4885
US-20080311173-A1 IMPLANTABLE OR INSERTABLE MEDICAL DEVICES FOR CONTROLLED DELIVERY OF A THERAPEUTIC AGENT PAICS, MIF, PGF LMNA 1827/4885TSHR 2465/4885PRKCA 671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.