Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 10/20 | 0.46 |
| ▸ | CNR2 | P34972 | 10/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3824126 | 0.81 | CNR1 (0.41) | CNR1CNR2MAPTMEN1GAA | |
| SCHEMBL3818747 | 0.80 | CNR2 (0.47) | CNR1CNR2MAPTHTTSMN1; SMN2 | |
| SCHEMBL3824123 | 0.78 | CNR1 (0.41) | CNR1CNR2MAPTGHSR | |
| SCHEMBL8190064 | 0.74 | CYP3A4 (0.42) | CNR1CNR2MAPTMEN1KMT2A | |
| SCHEMBL4735258 | 0.73 | ALDH1A1 (0.52) | CNR2MAPTMEN1HTTKMT2A | |
| SCHEMBL4739106 | 0.73 | NPC1 (0.41) | CNR1CNR2MAPTMEN1KMT2A | |
| SCHEMBL4738668 | 0.73 | CNR2 (0.40) | CNR1CNR2MAPT | |
| SCHEMBL8184199 | 0.73 | MAPK14 (0.44) | CNR1CNR2MAPT | |
| SCHEMBL13603931 | 0.72 | NPC1 (0.45) | CNR1CNR2MAPTGAAHTT | |
| SCHEMBL4733577 | 0.72 | TLR7 (0.40) | CNR1CNR2MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091917-A1 | ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2009-08-26 | — | — | EP | claimed |
| WO-2008073934-A1 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |