Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8184199 | 0.81 | MAPK14 (0.44) | CYP3A4CNR2CNR1MAPTTP53 | |
| SCHEMBL4733577 | 0.81 | TLR7 (0.40) | CYP3A4CNR2CNR1MAPTTP53 | |
| SCHEMBL3818747 | 0.80 | CNR2 (0.47) | CYP3A4CNR2CNR1MAPTTP53 | |
| SCHEMBL4735258 | 0.80 | ALDH1A1 (0.52) | CYP3A4CNR2MAPTTP53LMNA | |
| SCHEMBL4739106 | 0.79 | NPC1 (0.41) | CYP3A4CNR2CNR1MAPTPDK1 | |
| SCHEMBL4738668 | 0.79 | CNR2 (0.40) | CYP3A4CNR2CNR1MAPTPDK1 | |
| SCHEMBL4736786 | 0.79 | OPRM1 (0.41) | CYP3A4CNR2CNR1PDK1GPBAR1 | |
| SCHEMBL3824123 | 0.78 | CNR1 (0.41) | CYP3A4CNR2CNR1MAPTLMNA | |
| SCHEMBL4736765 | 0.77 | CYP19A1 (0.43) | CNR2CNR1MAPTTP53 | |
| SCHEMBL4733672 | 0.76 | ALDH1A1 (0.44) | CNR2CNR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073936-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |