Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 9/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8184199 | 0.82 | MAPK14 (0.44) | CNR2CNR1MAPTCYP3A4PDK1 | |
| SCHEMBL4733577 | 0.81 | TLR7 (0.40) | CNR2CNR1CFTRMAPTCYP3A4 | |
| SCHEMBL8190064 | 0.79 | CYP3A4 (0.42) | CNR2CNR1MAPTCYP3A4PDK1 | |
| SCHEMBL3818747 | 0.78 | CNR2 (0.47) | CNR2CNR1MAPTCYP3A4 | |
| SCHEMBL4735258 | 0.78 | ALDH1A1 (0.52) | CNR2MAPTCYP3A4 | |
| SCHEMBL4739106 | 0.78 | NPC1 (0.41) | CNR2CNR1MAPTCYP3A4PDK1 | |
| SCHEMBL4736786 | 0.77 | OPRM1 (0.41) | CNR2CNR1CYP3A4PDK1GPBAR1 | |
| SCHEMBL3824123 | 0.77 | CNR1 (0.41) | CNR2CNR1MAPTCYP3A4MAPK14 | |
| SCHEMBL4734930 | 0.74 | ALDH1A1 (0.45) | CNR2CNR1MAPTCYP3A4CASP3 | |
| SCHEMBL3818751 | 0.73 | CNR1 (0.46) | CNR2CNR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |