Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3854862 | 0.75 | HTT (0.40) | PARP1SMN1; SMN2HTTCDC7 | |
| SCHEMBL1622376 | 0.72 | RAB9A (0.56) | NPC1RAB9ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL23864607 | 0.69 | HPGD (0.49) | NPC1RAB9AKDM4EHSD17B2HSD17B1 | |
| SCHEMBL3215959 | 0.69 | HSD17B2 (0.60) | HSD17B2HSD17B1MTNR1AMTNR1BHTR1A | |
| SCHEMBL28382188 | 0.69 | PARP1 (0.56) | PARP1TP53HSD17B2HSD17B1MTNR1A | |
| SCHEMBL3227796 | 0.69 | HSD17B2 (0.58) | HSD17B2HSD17B1MTNR1AMTNR1BHTR1A | |
| SCHEMBL3219074 | 0.69 | HSD17B2 (0.58) | HSD17B2HSD17B1MTNR1AMTNR1BHTR1A | |
| SCHEMBL7614229 | 0.68 | MTNR1A (0.48) | PARP1RAB9AKDM4EHSD17B2HSD17B1 | |
| SCHEMBL28658410 | 0.68 | RAB9A (0.53) | PARP1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL28164220 | 0.68 | POLB (0.49) | TP53MAPTHSD17B2HSD17B1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2062050-A2 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | Senomyx, Inc. (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008154221-A2 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | SENOMYX, INC. (US) | 2008-12-18 | — | — | WO | disclosed |