Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 11/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1548437 | 0.80 | MTNR1B (0.55) | HPGDKDM4EMTNR1AMTNR1BHSD17B2 | |
| SCHEMBL23864289 | 0.78 | HIF1A (0.43) | HPGDKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL23864713 | 0.77 | KDM4E (0.36) | HPGDKDM4EALDH1A1MAPK1 | |
| SCHEMBL23864419 | 0.76 | CRHBP (0.37) | HPGDKDM4ERAB9AALDH1A1 | |
| SCHEMBL23864250 | 0.76 | LOXL2 (0.39) | RAB9AALDH1A1CYP3A4 | |
| SCHEMBL23864317 | 0.75 | CASP3 (0.36) | HPGDKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL3215959 | 0.74 | HSD17B2 (0.60) | MTNR1AMTNR1BHSD17B2HSD17B1 | |
| SCHEMBL23864569 | 0.74 | LMNA (0.40) | HPGDNPC1RAB9AALDH1A1 | |
| SCHEMBL23864351 | 0.74 | POLB (0.43) | HPGDALDH1A1 | |
| SCHEMBL3227796 | 0.73 | HSD17B2 (0.58) | MTNR1AMTNR1BHSD17B2HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968330-B1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | SCRIPPS RESEARCH INST (US) | 2021-09-29 | — | — | EP | disclosed |