Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1364078 | 0.98 | TSHR (0.37) | TSHRABCC4MAPTABHD16AALDH1A1 | |
| SCHEMBL3798152 | 0.98 | TSHR (0.37) | TSHRABCC4MAPTABHD16AALDH1A1 | |
| SCHEMBL3981398 | 0.96 | TSHR (0.33) | TSHRABCC4MAPTABHD16AALDH1A1 | |
| SCHEMBL3977462 | 0.89 | FAAH (0.38) | TSHRABCC4MAPTALDH1A1FAAH | |
| SCHEMBL5501614 | 0.83 | FAAH (0.31) | ABCC4MAPTABHD16AFAAH | |
| SCHEMBL28559593 | 0.82 | — | — | |
| SCHEMBL9334026 | 0.81 | TSHR (0.39) | TSHRABHD16AFAAH | |
| SCHEMBL5501498 | 0.81 | FAAH (0.31) | FAAH | |
| SCHEMBL1364944 | 0.80 | FAAH (0.34) | FAAH | |
| SCHEMBL12395555 | 0.77 | DAGLA (0.44) | ABCC4MAPTABHD16A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383834-B2 | Process for preparing unsaturated lactones | SYMRISE AG (DE) | 2013-02-26 | — | — | US | disclosed |
| US-20090306411-A1 | PROCESS FOR PREPARING UNSATURATED LACTONES | SYMRISE GMBH & CO. KG (DE) | 2009-12-10 | — | — | US | disclosed |
| WO-2005113533-A9 | PROCESS FOR PREPARING UNSATURATED LACTONES | SYMRISE GMBH & CO. KG (DE) | 2009-09-24 | — | — | WO | disclosed |
| EP-1747211-B1 | PROCESS FOR PREPARING UNSATURATED LACTONES | SYMRISE GMBH & CO KG (DE) | 2009-08-26 | — | — | EP | disclosed |
| EP-1747211-A1 | PROCESS FOR PREPARING UNSATURATED LACTONES | Akzo Nobel N.V. (NL) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005113533-A1 | PROCESS FOR PREPARING UNSATURATED LACTONES | SYMRISE GMBH & CO. KG (DE) | 2005-12-01 | — | — | WO | disclosed |
| EP-0889945-A1 | FRAGRANT MACROCYCLIC LACTONES | FIRMENICH SA (CH) | 1999-01-13 | — | — | EP | disclosed |
| WO-1997032948-A1 | FRAGRANT MACROCYCLIC LACTONES | FIRMENICH S.A. (CH) | 1997-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306411-A1 | PROCESS FOR PREPARING UNSATURATED LACTONES | ALOX5, ALOX12, ALOX15 | TSHR 3488/4885ABCC4 4129/4885MAPT 4839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.