SCHEMBL7208819

SCHEMBL7208819

Cl[Zr](Cl)(C1C=Cc2ccccc21)(C1C=Cc2ccccc21)=[Si](Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.38
SIGMAR1 Q99720 6/20 0.35
HTR2A P28223 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7643746 0.81 HTR2A (0.37) HTR6SIGMAR1HTR2A
SCHEMBL7639449 0.79 HTR2A (0.35) HTR6SIGMAR1HTR2A
SCHEMBL547453 0.76 HTR2A (0.34) HTR6HTR2A
SCHEMBL376490 0.76 HTR2A (0.36) HTR6SIGMAR1HTR2A
SCHEMBL618391 0.74 HTR6 (0.33) HTR6SIGMAR1HTR2A
SCHEMBL7642384 0.74 RET (0.36) HTR6SIGMAR1HTR2A
SCHEMBL8676857 0.74 HTR2A (0.33) HTR6SIGMAR1HTR2A
SCHEMBL7772297 0.74 SIGMAR1 (0.36) HTR6SIGMAR1HTR2A
SCHEMBL4445238 0.73 SIGMAR1 (0.35) HTR6SIGMAR1HTR2A
SCHEMBL3820447 0.73 SIGMAR1 (0.35) HTR6SIGMAR1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0891382-B1 ALPHA-OLEFIN-CYCLOOLEFIN COPOLYMERS AND PROCESS FOR THEIR PRODUCTION TEIJIN LTD (JP) 2003-05-28 EP disclosed
US-6476153-B2 INCLUDES A STEP OF DISTILLING UNREACTED DICYCLOPENTADIENE OR HYDROGENATED PRODUCT THEREOF, TETRAHYDRODICYCLOPENTADIENE FROM A MIXTURE OF THE COPOLYMER OR ITS HYDROGENATED PRODUCT IN THE PRESENCE OF A HIGH BOILING HYDROCARBON SOLVENT TEIJIN LIMITED (JP) 2002-11-05 US disclosed
US-6388032-B1 SEPARATION BY FILTRATION TEIJIN LIMITED (JP) 2002-05-14 US disclosed
US-20010009950-A1 Process for producing hydrogenated alpha-olefin- dicyclopentadiene copolymer, method for molding the same and optical material HASHIDZUME KIYONARI (JP) 2001-07-26 US disclosed
US-6232407-B1 MELT PROCESSABILITY TEIJIN LIMITED (JP) 2001-05-15 US disclosed
US-6191243-B1 ADDITION COPOLYMER HAVING HIGH DEGREE OF ALTERNATING ACYCLIC OLEFIN-DICYCLOPENTADIENE UNITS; OPTICAL RECORDING MEDIA SUBSTRATES TEIJIN LIMITED (JP) 2001-02-20 US disclosed
EP-1028128-A1 CYCLOOLEFIN POLYMER REDUCED IN CATALYST RESIDUE CONTENT, USE THEREOF, AND PROCESS FOR PRODUCING THE SAME TEIJIN LIMITED (JP) 2000-08-16 EP disclosed
EP-0964005-A1 Process for producing hydrogenated alpha-olefin-dicyclopentadiene copolymer, method for molding the same and optical material TEIJIN LIMITED (JP) 1999-12-15 EP disclosed
EP-0891382-A1 ALPHA-OLEFIN-CYCLOOLEFIN COPOLYMERS AND PROCESS FOR THEIR PRODUCTION TEIJIN LIMITED (JP) 1999-01-20 EP disclosed
WO-1998033830-A1 ALPHA-OLEFIN-CYCLOOLEFIN COPOLYMERS AND PROCESS FOR THEIR PRODUCTION TEIJIN LIMITED (JP) 1998-08-06 WO disclosed