Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7243552 | 0.79 | SMN1; SMN2 (0.33) | NPC1RAB9ASMN1; SMN2HPGDPOLB | |
| Hydrochloric Acid SCHEMBL8162033 | 0.71 | NPC1 (0.36) | NPC1RAB9ASMN1; SMN2HPGDPOLB | |
| Hydrochloric Acid SCHEMBL7635805 | 0.70 | SMN1; SMN2 (0.36) | NPC1RAB9ASMN1; SMN2HPGDPOLB | |
| Dibenzoylmethane SCHEMBL28456473 | 0.69 | KMT2A (0.59) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| Hydrochloric Acid SCHEMBL7247941 | 0.69 | RAB9A (0.32) | NPC1RAB9ASMN1; SMN2HPGDPOLB | |
| SCHEMBL15012686 | 0.69 | NPC1 (0.36) | NPC1RAB9ASMN1; SMN2HPGDPOLB | |
| Hydrochloric Acid SCHEMBL713800 | 0.68 | BCAT2 (0.38) | NPC1RAB9ASMN1; SMN2HPGDPOLB | |
| Hydrochloric Acid SCHEMBL5852836 | 0.67 | PTGS2 (0.36) | NPC1RAB9ASMN1; SMN2HPGDPOLB | |
| SCHEMBL6439072 | 0.67 | BCAT2 (0.40) | NPC1RAB9ASMN1; SMN2HPGDPOLB | |
| Hydrochloric Acid SCHEMBL9568471 | 0.66 | SMN1; SMN2 (0.34) | NPC1RAB9ASMN1; SMN2HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9200093-B2 | Polymerization method using surfactant-containing particle | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-12-01 | — | — | US | disclosed |
| US-20140288251-A1 | POLYMERIZATION METHOD USING SURFACTANT-CONTAINING PARTICLE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-09-25 | — | — | US | disclosed |
| EP-1113026-B1 | Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL CO (JP) | 2009-12-09 | — | — | EP | disclosed |
| US-7595371-B2 | Ethylene-α-olefin copolymer and food packaging material | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-09-29 | — | — | US | disclosed |
| EP-1113025-B1 | Catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL CO (JP) | 2009-09-02 | — | — | EP | disclosed |
| EP-2048167-A2 | First catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer | Sumitomo Chemical Company, Limited (JP) | 2009-04-15 | — | — | EP | disclosed |
| EP-2048168-A2 | Process for producing catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer | Sumitomo Chemical Company, Limited (JP) | 2009-04-15 | — | — | EP | disclosed |
| EP-2048170-A2 | Second catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer | Sumitomo Chemical Company, Limited (JP) | 2009-04-15 | — | — | EP | disclosed |
| EP-2048169-A2 | Third catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer | Sumitomo Chemical Company, Limited (JP) | 2009-04-15 | — | — | EP | disclosed |
| US-7485687-B2 | Melt flow rate of 0.01 to 100 g/10 min, an activation energy of flow of 50 kJ/mol or more, molecular weight distribution measured by a gel permeation chromatography of 3 or more and minute defects of 2000/m2 or less; molding materials | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-02-03 | — | — | US | disclosed |
| US-20010041775-A1 | Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-11-15 | — | — | US | disclosed |
| US-20010031834-A1 | Using coordination catalyst; flexibility, elasticity; molding materials | CHISSO CORPORATION | 2001-10-18 | — | — | US | disclosed |
| US-20010025085-A1 | Aromatic vinyl resin material and molded products thereof | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2001-09-27 | — | — | US | disclosed |
| US-20010020075-A1 | Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-09-06 | — | — | US | disclosed |
| EP-1113025-A2 | Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-07-04 | — | — | EP | disclosed |
| EP-1113026-A2 | Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-07-04 | — | — | EP | disclosed |
| US-6207753-B1 | RESIN MATERIALS FOR PRODUCING MOLDED PRODUCTS ENDOWED WITH EXCELLENT HEAT RESISTANCE, SOLVENT RESISTANCE, TOUGHNESS, TENSILE ELONGATION AND TRANSPARENCY | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |
| EP-0985673-A2 | Modified aluminium oxy compound, polymerization catalyst and process for producing olefin polymer and alkenyl aromatic hydrocarbon polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-03-15 | — | — | EP | disclosed |
| EP-0911349-A1 | Aromatic vinyl resin material and molded products thereof | Idemitsu Petrochemical Co., Ltd. (JP) | 1999-04-28 | — | — | EP | disclosed |
| EP-0911346-A2 | Ethylene copolymer and aromatic vinyl graft copolymer and method for producing the same | Idemitsu Petrochemical Co., Ltd. (JP) | 1999-04-28 | — | — | EP | disclosed |