SCHEMBL382206

SCHEMBL382206

O=C(O)COC1CCN(c2ccc(C(F)(F)F)cc2)CC1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.56
ITGB3 P05106 4/20 0.55
ITGA2B P08514 4/20 0.55
CA12 O43570 1/20 0.48
CA2 P00918 1/20 0.48
CA9 Q16790 1/20 0.48
AKR1C3 P42330 1/20 0.46
LIPG Q9Y5X9 6/20 0.46
LPL P06858 1/20 0.46
DEGS1 O15121 1/20 0.45
CHRM2 P08172 1/20 0.44
ME2 P23368 1/20 0.44
ME1 P48163 1/20 0.44
ME3 Q16798 1/20 0.44
PPARD Q03181 1/20 0.44
PPARA Q07869 1/20 0.44
LIPC P11150 1/20 0.43
ENPP2 Q13822 1/20 0.43
CYP11B1 P15538 1/20 0.43
CYP11B2 P19099 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1410148 0.92 NOTUM (0.60) NOTUMITGB3ITGA2BLIPGLPL
SCHEMBL381997 0.84 CYP11B1 (0.48) NOTUMCA12CA2CA9AKR1C3
SCHEMBL14167545 0.82 ITGB3 (0.55) ITGB3ITGA2BAKR1C3
SCHEMBL12809981 0.81 NOTUM (0.55) NOTUMCA12CA2CA9LIPG
SCHEMBL23086624 0.80 ITGB3 (0.53) ITGB3ITGA2B
SCHEMBL1410218 0.79 FFAR4 (0.52) NOTUMLIPGLPLLIPC
SCHEMBL1409535 0.79 FFAR4 (0.52) NOTUMLIPGLPLLIPC
SCHEMBL31464977 0.79 GPR119 (0.48) ITGB3ITGA2BLIPGCHRM2PPARD
SCHEMBL1410475 0.79 FFAR4 (0.52) NOTUMLIPGLPLLIPC
SCHEMBL12508738 0.79 NOTUM (0.59) NOTUMCA12CA2CA9CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9663657-B2 Moisture curable organopolysiloxane compositions MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2017-05-30 US claimed
US-9493691-B2 Moisture curable organopolysiloxane compositions MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2016-11-15 US claimed
US-20160060494-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS INC. 2016-03-03 US claimed
EP-2969996-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITIONS Momentive Performance Materials Inc. (US) 2016-01-20 EP claimed
US-20140350175-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS INC. 2014-11-27 US claimed
EP-2791198-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITIONS Momentive Performance Materials Inc. (US) 2014-10-22 EP claimed
WO-2014163917-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2014-10-09 WO claimed
WO-2013090127-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2013-06-20 WO claimed
EP-4385086-B1 SECONDARY BATTERY PACK WITH IMPROVED THERMAL MANAGEMENT ELKEM SILICONES USA CORP (US) 2025-08-13 EP disclosed
EP-4399245-A1 NON-SAG COMPOSITION Momentive Performance Materials Inc. (US) 2024-07-17 EP disclosed
EP-4385086-A2 SECONDARY BATTERY PACK WITH IMPROVED THERMAL MANAGEMENT Elkem Silicones USA Corp. (US) 2024-06-19 EP disclosed
WO-2023039116-A1 NON-SAG COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2023-03-16 WO disclosed
US-20230083453-A1 NON-SAG COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. 2023-03-16 US disclosed
US-20230060699-A1 SECONDARY BATTERY PACK WITH IMPROVED THERMAL MANAGEMENT Elkem Silicones USA Corp. 2023-03-02 US disclosed
EP-2408742-A1 ANTHELMINTIC AGENTS AND THEIR USE Intervet International B.V. (NL) 2012-01-25 EP disclosed
US-20110319393-A1 ANTHELMINTIC AGENTS AND THEIR USE INTERVET INTERNATIONAL B.V. (NL) 2011-12-29 US disclosed
US-20110319393-A1 ANTHELMINTIC AGENTS AND THEIR USE INTERVET INTERNATIONAL B.V. (NL) 2011-12-29 US disclosed
US-20110319393-A1 ANTHELMINTIC AGENTS AND THEIR USE INTERVET INTERNATIONAL B.V. (NL) 2011-12-29 US disclosed
WO-2010115688-A1 ANTHELMINTIC AGENTS AND THEIR USE INTERVET INTERNATIONAL B.V. (NL) 2010-10-14 WO disclosed
WO-2010115688-A1 ANTHELMINTIC AGENTS AND THEIR USE INTERVET INTERNATIONAL B.V. (NL) 2010-10-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110319393-A1 ANTHELMINTIC AGENTS AND THEIR USE ACHE, ABCB11, MPO NOTUM 157/4885ITGB3 3524/4885ITGA2B 4406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.