SCHEMBL3822458

SCHEMBL3822458

[c]1c(-c2ccc3c4ccccc4c4ccccc4c3c2)cccc1-c1ccc2c3ccccc3c3ccccc3c2c1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ HPRT1 P00492 3/20 0.33
▸ ALDH1A1 P00352 1/20 0.31
▸ CYP1A2 P05177 1/20 0.31
▸ THRB P10828 1/20 0.31
▸ HPGD P15428 1/20 0.31
▸ HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1371507 0.78 HPRT1 (0.31) HPRT1
SCHEMBL4133589 0.77 HPRT1 (0.45) HPRT1ALDH1A1CYP1A2THRBHPGD
SCHEMBL3818941 0.77 KIF11 (0.39) —
SCHEMBL311937 0.75 ESR1 (0.46) HPRT1
SCHEMBL311659 0.75 ESR1 (0.46) HPRT1
SCHEMBL3089094 0.73 HSD17B1 (0.50) ALDH1A1CYP1A2HPGDHSD17B10
SCHEMBL23432303 0.71 MEN1 (0.48) ALDH1A1
SCHEMBL20431790 0.71 MEN1 (0.48) ALDH1A1
SCHEMBL22173462 0.71 MEN1 (0.48) ALDH1A1
SCHEMBL14958604 0.71 MEN1 (0.48) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10381579-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-13 — — US claimed
US-20150249225-A1 STABILITY OLED MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-09-03 — — US claimed
US-9051344-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-06-09 — — US claimed
EP-1878053-B1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORP (US) 2009-08-26 — — EP claimed
US-11404650-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-08-02 — — US disclosed
US-10381579-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-13 — — US disclosed
US-20150249225-A1 STABILITY OLED MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-09-03 — — US disclosed
US-9051344-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-06-09 — — US disclosed
US-7902374-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2011-03-08 — — US disclosed
EP-1878053-B1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORP (US) 2009-08-26 — — EP disclosed
WO-2008054584-A1 IMPROVED STABILITY OLED MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2008-05-08 — — WO disclosed
EP-1878053-A1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY Universal Display Corporation (US) 2008-01-16 — — EP disclosed
US-20070088167-A1 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION 2007-04-19 — — US disclosed
WO-2006121811-A1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORPORATION (US) 2006-11-16 — — WO disclosed
US-20060251923-A1 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION 2006-11-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11404650-B2 Stability OLED materials and devices OCIAD2, OCIAD1, OSBP2 HPRT1 199/4885ALDH1A1 1780/4885CYP1A2 1075/4885
US-10381579-B2 Stability OLED materials and devices OCIAD2, OCIAD1, OSBP2 HPRT1 198/4885ALDH1A1 1804/4885CYP1A2 1061/4885
US-20150249225-A1 STABILITY OLED MATERIALS AND DEVICES OCIAD2, OCIAD1, OSBP2 HPRT1 198/4885ALDH1A1 1804/4885CYP1A2 1061/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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