SCHEMBL3822609

SCHEMBL3822609

O=C1c2ccc(C(c3ccc4c(c3)C(=O)N(O)C4=O)(C(F)(F)F)C(F)(F)F)cc2C(=O)N1O

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.39
ESR2 Q92731 3/20 0.39
CA9 Q16790 4/20 0.37
CA12 O43570 3/20 0.37
CA1 P00915 3/20 0.37
NR1H2 P55055 1/20 0.36
NR1H3 Q13133 1/20 0.36
ERCC1 P07992 2/20 0.35
FEN1 P39748 2/20 0.35
ERCC4 Q92889 2/20 0.35
CA2 P00918 2/20 0.33
CYP1A2 P05177 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
TSHR P16473 1/20 0.33
ALOX12 P18054 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KDM4E B2RXH2 1/20 0.32
AADAT Q8N5Z0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24380219 0.89 KDM4E (0.38) ESR1ESR2CA9CA12CA1
SCHEMBL4549126 0.82 ALDH1A1 (0.47) NR1H2NR1H3POLBMAPTKDM4E
SCHEMBL9550303 0.79 ESR1 (0.33) ESR1ESR2CA9CA12CA1
SCHEMBL18391128 0.79 KDM4E (0.59) CA9CA1CA2POLBTSHR
SCHEMBL15479586 0.78 POLB (0.50) CA9CA12CA1CA2POLB
SCHEMBL6938706 0.78 CA9 (0.45) ESR1ESR2CA9CA12CA1
SCHEMBL25969208 0.78 ESR1 (0.64) ESR1ESR2CA9CA12CA1
SCHEMBL29906097 0.77 ESR1 (0.55) ESR1ESR2CA9CA12CA1
SCHEMBL13460950 0.77 ESR1 (0.55) ESR1ESR2CA9CA12CA1
SCHEMBL859762 0.77 CA9 (0.37) ESR1ESR2CA9CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1449833-B1 BISIMIDE COMPOUND, ACID GENERATOR AND RESIST COMPOSITION EACH CONTAINING THE SAME, AND METHOD OF FORMING PATTERN FROM THE COMPOSITION WAKO PURE CHEM IND LTD (JP) 2009-09-09 EP disclosed
US-7374857-B2 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2008-05-20 US disclosed
US-20050038261-A1 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2005-02-17 US disclosed
EP-1449833-A1 BISIMIDE COMPOUND, ACID GENERATOR AND RESIST COMPOSITION EACH CONTAINING THE SAME, AND METHOD OF FORMING PATTERN FROM THE COMPOSITION Wako Pure Chemical Industries, Ltd. (JP) 2004-08-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050038261-A1 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition ASIC1, GAR1, RER1 ESR1 2503/4885ESR2 2940/4885CA9 801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.