Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | MLNR | O43193 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3826558 | 0.94 | RAB9A (0.49) | RAB9AALDH1A1NPC1RECQLPDPK1 | |
| SCHEMBL3077522 | 0.83 | TSHR (0.59) | RAB9AALDH1A1NPC1PDPK1MAPT | |
| SCHEMBL7050949 | 0.83 | TSHR (0.59) | RAB9AALDH1A1NPC1PDPK1MAPT | |
| SCHEMBL2634592 | 0.82 | ALDH1A1 (0.67) | RAB9AALDH1A1NPC1RECQLMAPT | |
| SCHEMBL2633940 | 0.82 | ALDH1A1 (0.67) | RAB9AALDH1A1NPC1RECQLMAPT | |
| SCHEMBL2633915 | 0.82 | ALDH1A1 (0.67) | RAB9AALDH1A1NPC1RECQLMAPT | |
| SCHEMBL26820508 | 0.82 | KMT2A (0.58) | RAB9AALDH1A1NPC1PDPK1MAPT | |
| SCHEMBL29110675 | 0.82 | KMT2A (0.58) | RAB9AALDH1A1NPC1PDPK1MAPT | |
| SCHEMBL11523999 | 0.81 | APAF1 (0.52) | RAB9AALDH1A1NPC1RECQLPDPK1 | |
| SCHEMBL29110668 | 0.79 | PDPK1 (0.60) | PDPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010294-B1 | ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2015-12-02 | — | — | EP | claimed |
| US-7906684-B2 | Antioxidants | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-03-15 | — | — | US | claimed |
| US-20090246158-A1 | ANTIOXIDANTS | MERCK PATENT GESELLSCHAFT (DE) | 2009-10-01 | — | — | US | claimed |
| EP-2010294-A1 | ANTIOXIDANTS | Merck Patent GmbH (DE) | 2009-01-07 | — | — | EP | claimed |
| WO-2007121845-A1 | ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2007-11-01 | — | — | WO | claimed |
| EP-2010294-B1 | ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2015-12-02 | — | — | EP | disclosed |
| US-7906684-B2 | Antioxidants | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-03-15 | — | — | US | disclosed |
| US-20090246158-A1 | ANTIOXIDANTS | MERCK PATENT GESELLSCHAFT (DE) | 2009-10-01 | — | — | US | disclosed |
| EP-2010294-A1 | ANTIOXIDANTS | Merck Patent GmbH (DE) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007121845-A1 | ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2007-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090246158-A1 | ANTIOXIDANTS | LPO, GPX1, GPX4 | RAB9A 1823/4885ALDH1A1 408/4885NPC1 680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.