Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | CA4 | P22748 | 4/20 | 0.39 |
| ▸ | CA6 | P23280 | 4/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | CA5A | P35218 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.39 |
| ▸ | CA3 | P07451 | 2/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.39 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5808148 | 0.84 | MAOB (0.47) | CA1CA2CA12CA9CA4 | |
| SCHEMBL7949512 | 0.82 | TDP2 (0.39) | PTGS2LMNAALDH1A1L3MBTL1KDM4E | |
| SCHEMBL3826489 | 0.80 | CA1 (0.38) | CA1CA2CA12CA9CA4 | |
| Hydrochloric Acid SCHEMBL5805304 | 0.80 | PTGS2 (0.38) | CA1CA2CA12CA9CA4 | |
| SCHEMBL3853255 | 0.79 | LRRK2 (0.44) | CA1CA2CA12CA9CA4 | |
| SCHEMBL3819217 | 0.79 | PKM (0.44) | CA1CA2CA12CA9PTGS2 | |
| SCHEMBL8976123 | 0.77 | CA2 (0.52) | CA1CA2CA12CA9CA4 | |
| SCHEMBL28134095 | 0.77 | MAOB (0.49) | CA1CA2CA12CA9CA4 | |
| SCHEMBL4073856 | 0.75 | LRRK2 (0.51) | CA1CA2CA12CA9CA4 | |
| Hydrochloric Acid SCHEMBL5808225 | 0.75 | MAOB (0.44) | CA1CA2CA12CA9CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009129365-A1 | CATHEPSIN C INHIBITORS | GLAXO GROUP LIMITED (GB) | 2009-10-22 | — | — | WO | claimed |