Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 4/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382399 | 0.88 | ITGB3 (0.40) | GRIN2BTP53KMT2ALMNACCNT1 | |
| SCHEMBL381718 | 0.86 | ALDH1A1 (0.38) | GRIN2BLMNACCNT1CCNA2CDK2 | |
| SCHEMBL383135 | 0.85 | ITGB3 (0.43) | ADRA2AITGB3ITGAV | |
| SCHEMBL382612 | 0.84 | GAA (0.37) | GRIN2BPRMT5MEN1KMT2ALMNA | |
| SCHEMBL383199 | 0.84 | DRD2 (0.36) | MEN1KMT2AL3MBTL1ADRA2AMCHR1 | |
| SCHEMBL6499236 | 0.83 | CNR1 (0.37) | GRIN2BKMT2ALMNAMAPTMAPK1 | |
| SCHEMBL382792 | 0.83 | ITGB3 (0.35) | ADRA2AMCHR1ITGB3ITGAVHSD17B10 | |
| SCHEMBL382989 | 0.82 | ITGB3 (0.36) | GRIN2BPRMT5L3MBTL1LMNAMAPT | |
| SCHEMBL382332 | 0.80 | ITGB3 (0.37) | LMNAADRA2AMCHR1ITGB3ITGAV | |
| SCHEMBL381825 | 0.80 | EPHX2 (0.36) | MEN1KMT2AL3MBTL1CDK2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | claimed |
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |