SCHEMBL382465

SCHEMBL382465

C=Cc1c(C(=O)O)ccc2ccccc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
WDR5 P61964 1/20 0.59
LDHA P00338 1/20 0.58
NR4A1 P22736 1/20 0.53
NR4A2 P43354 1/20 0.53
NR4A3 Q92570 1/20 0.53
KDM4E B2RXH2 3/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
RAB9A P51151 2/20 0.48
NPC1 O15118 1/20 0.48
MITF O75030 1/20 0.48
MAPT P10636 1/20 0.48
KLF5 Q13887 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
CDC25B P30305 1/20 0.47
ERN1 O75460 1/20 0.44
ALDH1A1 P00352 3/20 0.44
HPGD P15428 3/20 0.44
LMNA P02545 1/20 0.44
CYP2D6 P10635 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL547877 0.84 WDR5 (0.61) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL27457193 0.78 PTPN1 (0.54) KDM4EMEN1KMT2AMAPTTDP1
SCHEMBL4383378 0.78 MEN1 (0.53) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL332990 0.78 CYP1A2 (0.50) WDR5KDM4EMAPTALDH1A1HPGD
Acrylic Acid SCHEMBL28745482 0.76 WDR5 (0.56) WDR5LDHANR4A1NR4A2NR4A3
Propene SCHEMBL27774593 0.76 WDR5 (0.56) WDR5LDHANR4A1NR4A2NR4A3
Acrylic Acid SCHEMBL27762972 0.76 ERN1 (0.42) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL4168177 0.76 WDR5 (0.51) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL10590856 0.76 RRM1 (0.40) WDR5LDHAMEN1KMT2AMAPT
SCHEMBL895573 0.75 WDR5 (1.00) WDR5LDHANR4A1NR4A2NR4A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107203109-B Toner and method for producing toner 佳能株式会社 2020-12-01 CN disclosed
CN-107037700-B Toner and image forming apparatus 佳能株式会社 2020-09-04 CN disclosed
US-10551758-B2 Toner CANON KABUSHIKI KAISHA (JP) 2020-02-04 US disclosed
US-20180329328-A1 TONER CANON KABUSHIKI KAISHA (JP) 2018-11-15 US disclosed
US-20180211828-A1 COMPOSITION FOR FORMING FILM FOR USE IN CLEANING SEMICONDUCTOR SUBSTRATE, AND CLEANING METHOD FOR SEMICONDUCTOR SUBSTRATE JSR CORPORATION (JP) 2018-07-26 US disclosed
US-9921501-B2 Toner and process for producing toner CANON KABUSHIKI KAISHA (JP) 2018-03-20 US disclosed
US-9897932-B2 Toner CANON KABUSHIKI KAISHA (JP) 2018-02-20 US disclosed
CN-107203109-A The manufacture method of toner and toner 佳能株式会社 2017-09-26 CN disclosed
US-20170269488-A1 TONER AND PROCESS FOR PRODUCING TONER CANON KABUSHIKI KAISHA (JP) 2017-09-21 US disclosed
US-9733584-B2 Toner CANON KABUSHIKI KAISHA (JP) 2017-08-15 US disclosed
US-20100203457-A1 PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-08-12 US disclosed
US-20100178617-A1 PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-07-15 US disclosed
US-20100178618-A1 PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-07-15 US disclosed
US-20090081595-A1 PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-03-26 US disclosed
US-20090011199-A1 Fluorine-Containing Compound, Fluorine-Containing Polymer, Negative-Type Resist Composition, and Patterning Process Using Same CENTRAL GLASS COMPANY, LIMITED (JP) 2009-01-08 US disclosed
EP-0849634-B1 Radiation sensitive resin composition JSR CORP (JP) 2004-03-31 EP disclosed
US-6322949-B2 SULFONIUM COMPOUND AS PHOTOACID GENERATOR JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 2001-11-27 US disclosed
US-20010014427-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 2001-08-16 US disclosed
US-6187504-B1 PHOTOSENSITIVE BLEND CONTAINING A NAPHTHALENE SULFONIUM SULFONATE DERIVATIVE PHOTOACID GENERATOR, RESIN HAVING ALKALI INSOLUBLE GROUPS CLEAVABLE BY ACID, AN ALKALI SOLUBLE RESIN AND A SOLUBILITY CONTROL AGENT; POSITIVES, RESOLUTION JSR CORPORATION (JP) 2001-02-13 US disclosed
EP-0849634-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-06-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090011199-A1 Fluorine-Containing Compound, Fluorine-Containing Polymer, Negative-Type Resist Composition, and Patterning Process Using Same FGFR2, RTF1, ADGRF1 WDR5 86/4885LDHA 4294/4885NR4A1 2593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.