Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | CKS1B | P61024 | 1/20 | 0.42 |
| ▸ | SKP1 | P63208 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383159 | 0.84 | ITGB3 (0.44) | ITGB3ITGAVITGA2BSFRP1GLA | |
| SCHEMBL383469 | 0.82 | CCR5 (0.42) | CCR5CKS1BSKP1SKP2KCNA3 | |
| SCHEMBL7664593 | 0.81 | CCR5 (0.44) | CCR5CKS1BSKP1SKP2KCNA3 | |
| SCHEMBL383583 | 0.79 | ITGB3 (0.61) | ITGB3ITGAVITGA2BSFRP1ALDH1A1 | |
| SCHEMBL382571 | 0.79 | ITGB3 (0.42) | ITGB3ITGAVITGA2BSFRP1ALDH1A1 | |
| SCHEMBL7664581 | 0.78 | ITGB3 (0.64) | ITGB3ITGAVITGA2B | |
| SCHEMBL460323 | 0.78 | ITGB3 (0.41) | ITGB3ITGAVITGA2BSFRP1GLA | |
| SCHEMBL7664584 | 0.77 | CCR5 (0.42) | CCR5CKS1BSKP1SKP2KCNA3 | |
| SCHEMBL382658 | 0.76 | MAPT (0.40) | ITGB3ITGAVITGA2BALDH1A1MAPT | |
| SCHEMBL6499251 | 0.76 | SFRP1 (0.42) | ITGB3ITGAVITGA2BSFRP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |