Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19813740 | 0.83 | TDP1 (0.52) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL3871053 | 0.81 | CA2 (0.45) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL11125465 | 0.79 | CHRM1 (0.31) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL5789746 | 0.79 | TDP1 (0.37) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL240145 | 0.79 | TDP1 (0.37) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL7800234 | 0.78 | GABRP (0.41) | TDP1GABRPGABRDGABRA1GABRB1 | |
| Ammonia Solution, Strong SCHEMBL27753044 | 0.77 | TDP1 (0.39) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL2354887 | 0.77 | LMNA (0.36) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL11382908 | 0.77 | TDP1 (0.36) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL566390 | 0.76 | LMNA (0.39) | TDP1CHRM1AKR1A1CHRM3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219626-A2 | Film-forming compositions comprising polyglutarimide | International Business Machines Corporation (US) | 1987-04-29 | — | — | EP | claimed |
| WO-2019025575-A1 | PROCESSES FOR PREPARING COMPLEXES COMPRISING RHODIUM(II) AND CARBOXYLATE LIGANDS | STOCKHOLM UNIVERSITY HOLDING AB (SE) | 2019-02-07 | — | — | WO | disclosed |
| CN-104335120-B | Photosensitive resin composition, pattern formed using the same, and display panel including the same | 株式会社LG化学 | 2018-04-03 | — | — | CN | disclosed |
| WO-2017129991-A2 | PROCESSES FOR PREPARING STERICALLY CONGESTED DICARBOXYLIC ACID LIGANDS AND PRODUCTS THEREOF | STOCKHOLM UNIVERSITY HOLDING AB (SE) | 2017-08-03 | — | — | WO | disclosed |
| US-9341946-B2 | Photosensitive resin composition, pattern formed using same and display panel comprising same | LG CHEM, LTD. (KR) | 2016-05-17 | — | — | US | disclosed |
| US-20150125789-A1 | PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMED USING SAME AND DISPLAY PANEL COMPRISING SAME | LG CHEM, LTD. (KR) | 2015-05-07 | — | — | US | disclosed |
| CN-104335120-A | Photosensitive resin composition, pattern formed using the same, and display panel including the same | LG CHEMICAL LTD | 2015-02-04 | — | — | CN | disclosed |
| US-8716335-B2 | Substituted benzofurans, benzothiophenes, benzoselenophenes and indoles and their use as tubulin polymerisation inhibitors | BIONOMICS LIMITED (AU) | 2014-05-06 | — | — | US | disclosed |
| US-20120214770-A1 | SUBSTITUTED BENZOFURANS, BENZOTHIOPHENES, BENZOSELENOPHENES AND INDOLES AND THEIR USE AS TUBULIN POLYMERISATION INHIBITORS | BIONOMICS LIMITED (AU) | 2012-08-23 | — | — | US | disclosed |
| EP-1874784-B1 | IONIC LIQUID | UNIV BREMEN (DE) | 2009-08-26 | — | — | EP | disclosed |
| WO-2006011647-A1 | POLYMERIZABLE COMPOSITION, OPTICALLY ANISOTROPIC LAYER AND METHOD FOR MANUFACTURING THEREOF, OPTICAL COMPENSATORY ELEMENT, LIQUID CRYSTAL DISPLAY AND LIQUID CRYSTAL PROJECTOR | FUJIFILM CORPORATION (JP) | 2006-02-02 | — | — | WO | disclosed |
| US-5225529-A | Central nervous system disorders such as Alzheimer*s disease | FARMHISPANIA S.A. (ES) | 1993-07-06 | — | — | US | disclosed |
| US-5049566-A | Imidazole [4,5-c] pyridine derivatives having gastric acid antisecretory activity and pharmaceutical compositions containing them | CHIESI FARMACEUTIC S.P.A. (IT) | 1991-09-17 | — | — | US | disclosed |
| EP-0381070-A1 | Synthetic amphiphilic glycoconjugates for neurological use | FARMHISPANIA S.A. (ES) | 1990-08-08 | — | — | EP | disclosed |
| US-4937367-A | Process for the preparation of intermediates for the synthesis of fosfomycin | ZAMBON GROUP S.P.A. (IT) | 1990-06-26 | — | — | US | disclosed |
| US-4873337-A | N-substituted derivatives of 2-(pyridylalkenesulfinyl) benzimidazoles as gastric antisecretory agents | THE UPJOHN COMPANY (US) | 1989-10-10 | — | — | US | disclosed |
| EP-0299484-A1 | Process for the preparation of intermediates for the synthesis of fosfomycin | ZAMBON GROUP S.p.A. (IT) | 1989-01-18 | — | — | EP | disclosed |
| EP-0219626-A2 | Film-forming compositions comprising polyglutarimide | International Business Machines Corporation (US) | 1987-04-29 | — | — | EP | disclosed |
| EP-0176308-A2 | 2-(Pyridylalkylenesulfinyl) benzimidazoles | THE UPJOHN COMPANY (US) | 1986-04-02 | — | — | EP | disclosed |
| US-4307112-A | 9-Deoxy-9A-methylene isosteres of PGI2 and process for their preparation | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120214770-A1 | SUBSTITUTED BENZOFURANS, BENZOTHIOPHENES, BENZOSELENOPHENES AND INDOLES AND THEIR USE AS TUBULIN POLYMERISATION INHIBITORS | TUBB1, TUBB3, TUBB | TDP1 661/4885CHRM1 4691/4885AKR1A1 3663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.